In the article we discuss problem of the coexisting ulcers of stomach and duodenum in patients with atherosclerosis on the coronary syndrome, depending on the localization of the ulcer. We have been revealed that worsening of the peptic ulcer causes increasing of the ischemia episodes and intensity of the cardiac rhythm disorders. Localization of the ulcers in the stomach has significant influence on algesic ischemia and postprandial ischemia, duodenal localization increasing night ischemia. Localization of the ulcers in the stomach, especially in the upper third cause disorders of the cardiac rhythm.

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