AI Article Synopsis
- A femoral head, despite showing no radiological signs, exhibited signs of osteonecrosis 54 years after significant radiation exposure to the right hip.
- The analysis revealed connective tissue infiltration in bone spaces, a notable presence of mast cells, and areas of cell resorption filled with mononucleated cells.
- Microradiographs indicated unusual hypercalcified lines in the bone, which could lead to questions about long-term effects of radiation on bone health, suggesting possible chronic issues like hypovascularity and disrupted remodeling.
Article Abstract
Despite the lack of radiological signs, a femoral head showed histological and microradiographical features of osteonecrosis, 54 years after massive irradiation of the right hip. Intertrabecular spaces were invaded by connectivo-vascular tissue with focal accumulation of mast cells, and several resorption foci were filled with mononucleated cells. Moreover, all the microradiographs showed peculiar hypercalcified lines, sometimes containing empty osteocytic lacunae, the origin of which is difficult to precise. This study suggests that massive irradiation of weight-bearing epiphyses may be responsible for particularly long-term hypovascularity, osteonecrosis and disturbed bone remodeling.
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| http://dx.doi.org/10.1007/BF02207666 | DOI Listing |
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