AI Article Synopsis
- The study used micro-focus X-ray fluoroscopy to observe and record the movement of cochlear implant electrodes during their insertion into human cadaver temporal bones.
- Fluoroscopy provided important insights into the design features of various electrode prototypes, particularly during the insertions of both Hybrid-L and Contour Advance enhanced (CAe) arrays.
- Real-time visual documentation helped validate the performance of newly designed intra-cochlear electrode arrays, ensuring they were positioned optimally within the cochlea.
Article Abstract
The aim of this study was to utilise micro-focus X-ray fluoroscopy for viewing electrode movement in the cochlea. Various prototypes of newly designed cochlear implant electrodes were evaluated during insertion studies on human cadaver temporal bones. The magnified fluoroscopic images were observed in real-time and recorded for retrospective studies. In 30 insertions of hearing preservation (Hybrid-L) arrays, fluoroscopy provided crucial information on the tip design, length of array and stiffening stylet. In 44 insertions of Contour Advance enhanced (CAe) arrays, the length, curvature, depth of insertion and degree of stiffness were assessed. CAe arrays were successfully inserted to the designated depth and positioned close to the modiolus. High quality micro-focus fluoroscopic images of electrode movement in the cochlea greatly assisted in the validation of newly designed intra-cochlear electrode arrays.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1179/cim.2009.10.Supplement-1.115 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Highly ionic conductive, elastic, and biocompatible double-network composite gel for epidermal biopotential monitoring and wearable sensing.
J Colloid Interface Sci
January 2025
School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China. Electronic address:
Soft ionic conductors are promising candidates for epidermal electrodes, flexible sensors, ionic skins, and other soft iontronic devices. However, their inadequate ionic conductivity and mechanical properties (such as toughness and adhesiveness) are still the main constraints for their wide applications in wearable bioelectronics. Herein, an all-biocompatible composite gel with a double-network (DN) strategy is proposed.
View Article and Find Full Text PDFLiquid Metal Elastomer-Based U-Shaped Electrode Flexible Strain Sensors with Enhanced Stability and Sensitivity.
ACS Appl Mater Interfaces
January 2025
College of Computer Science and Technology, Xi'an University of Science and Technology, Xi'an 710054, China.
Soft and stretchable strain sensors are crucial for applications in human-machine interfaces, flexible robotics, and electronic skin. Among these, capacitive strain sensors are widely used and studied; however, they face challenges due to material and structural constraints, such as low baseline capacitance and susceptibility to external interference, which result in low signal-to-noise ratios and poor stability. To address these issues, we propose a U-shaped electrode flexible strain sensor based on liquid metal elastomer (LME).
View Article and Find Full Text PDFModular DNA origami-based electrochemical detection of DNA and proteins.
Proc Natl Acad Sci U S A
January 2025
Department of Bioengineering, California Institute of Technology, Pasadena, CA 91125.
The diversity and heterogeneity of biomarkers has made the development of general methods for single-step quantification of analytes difficult. For individual biomarkers, electrochemical methods that detect a conformational change in an affinity binder upon analyte binding have shown promise. However, because the conformational change must operate within a nanometer-scale working distance, an entirely new sensor, with a unique conformational change, must be developed for each analyte.
View Article and Find Full Text PDFReprogrammable Flexible Piezoelectric Actuator Arrays with a High Degree of Freedom for Shape Morphing and Locomotion.
Soft Robot
January 2025
State Key Laboratory of Fluid Power and Mechatronic Systems, Zhejiang University, Hangzhou, China.
The high degree of freedom (DoF) shape morphing widely exists in biology for mimicry, camouflage, and locomotion. Currently, a lot of bionic soft/flexible actuators and robots with shape-morphing functions have been developed to realize conformity, grasp, and movement. Among these solutions, two-dimensional responsive materials and structures that can shape morph into different three-dimensional configurations are valuable for creating reversible high DoF shape morphing.
View Article and Find Full Text PDFSubthalamic nucleus deep brain stimulation in the beta frequency range boosts cortical beta oscillations and slows down movement.
J Neurosci
January 2025
Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225 Germany
Recordings from Parkinson's disease (PD) patients typically show strong beta-band oscillations (13-35Hz), which can be modulated by deep brain stimulation (DBS). While high-frequency DBS (>100Hz) ameliorates motor symptoms and reduces beta activity in basal ganglia and motor cortex, the effects of low-frequency DBS (<30Hz) are less clear. Clarifying these effects is relevant for the debate about the role of beta oscillations in motor slowing, which might be causal or epiphenomenal.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!