Objective: To compare the accuracy of four scales, and to determine the inter-rater reliability and the influence of schooling on Clock Drawing Test performance in screening for dementia in elderly with low educational level.
Design: Criterion validation, concurrent type.
Setting: Outpatient unit of Universidade do Estado do Rio de Janeiro Hospital, Brazil.
Participants: A total of 306 individuals (> or = 65 years) were assessed by a geriatrician and a neuropsychologist using functional and cognitive instruments. The diagnosis of dementia was established by consensus in a meeting between these professionals. Four different researchers blinded as to the cognitive status of the patients scored the Clock Drawing Test using Shulman's, Sunderland's, Manos', and Wolf-Klein's methods; and a fifth researcher assessed Manos' method for an inter-rater reliability study.
Results: The data of 211 individuals (< or = 4 years of schooling) were analyzed. The sensitivity and specificity of the four methods were similar (about 65%). The inter-rater reliability of Manos' method was excellent (ICC = 0.944). The areas under the ROC curves were small (0.657 to 0.681), and the differences between them were not statistically significant.
Conclusions: The Clock Drawing Test is a reliable but not valid test to screen for dementia in older outpatients with 4 or less years of formal schooling.
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http://dx.doi.org/10.1590/s1516-44462008000400002 | DOI Listing |
Geriatrics (Basel)
December 2024
Orthopedics and Trauma Surgery, University Hospital Düsseldorf, Moorenstraße 5, 40225 Düsseldorf, Germany.
Background: Post-operative delirium is a dreaded complication after surgery in older patients. The identification of risk factors for delirium and comprehensive geriatric assessment is an extensive part of recent research. However, the preoperative assessment of risk factors, such as impaired cognition, is frequently not standardized.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Department of Biosciences, Università degli Studi di Milano, 20133 Milan, Italy.
α-synuclein oligomers within synaptic terminals of autonomic fibers of the skin reliably discriminate Parkinson's disease (PD) patients from healthy controls. Nonetheless, the prognostic role of oligomers for disease progression is unknown. We explored whether α-synuclein oligomers evaluated as proximity ligation assay (PLA) score may predict the worsening of cognitive functions in patients with Parkinson's disease.
View Article and Find Full Text PDFProc Biol Sci
November 2024
Department of Evolutionary & Environmental Biology, Institute of Evolution, University of Haifa, Haifa 3498838, Israel.
The study of the circadian clock has greatly benefited from using as a model system. Yet accumulating evidence suggests that the fly might not be the canonical insect model. Here, I have analysed the circadian transcriptome of the jewel wasp by using RNA-seq in both constant darkness and constant light (in contrast to flies, the wasps are rhythmic under continuous light).
View Article and Find Full Text PDFNeuroSci
October 2024
Clinical Psychology Service, IRCCS Policlinico San Donato, San Donato Milanese, 20097 Milan, Italy.
Background: Aortic valve stenosis (AVS) is a common valvular heart disease affecting millions of people worldwide. It leads to significant neurocognitive and neuropsychological impairments, impacting patients' quality of life.
Objective: The objective of this article is to identify and discuss the potential neurocognitive effects on patients with aortic stenosis before and after undergoing surgical aortic valve replacement (SAVR).
Ann Vasc Surg
November 2024
University of Florida, Department of Vascular Surgery and Endovascular Therapy, Gainesville, FL. Electronic address:
Background: Patients' capacities to understand and act upon healthcare information is crucial to decision-making and high-quality care. Cognitive impairment (CI) has been associated with adverse outcomes across a range of diseases and surgeries. Despite the importance of CI, there is little to no information on its prevalence and severity in vascular surgery patients in the United States.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!