Antiphospholipid syndrome in a 21-year-old with Klinefelter syndrome.

J Clin Rheumatol

Rheumatology Service, Walter Reed Army Medical Center, NW, Washington, DC 20307, USA.

Published: February 2009

AI Article Synopsis

  • A patient with Klinefelter syndrome developed recurrent arterial thromboses due to antiphospholipid syndrome.
  • Previous cases have linked Klinefelter syndrome with systemic lupus erythematosus and related autoimmune issues, including antiphospholipid syndrome.
  • Doctors should be aware of potential autoimmune problems when treating Klinefelter syndrome patients who experience repeated thrombosis or signs of systemic autoimmune disorders.

Article Abstract

We describe a patient with Klinefelter syndrome presenting with recurrent arterial thromboses secondary to the antiphospholipid syndrome. Previous case reports noted association of Klinefelter syndrome with systemic lupus erythematosus including some cases with antiphospholipid syndrome. Clinicians should consider autoimmune processes, including the antiphospholipid syndrome, when patients with Klinefelter syndrome present with recurrent thrombosis or additional features of a systemic autoimmune disorder.

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Source
http://dx.doi.org/10.1097/rhu.0b013e31817de084DOI Listing

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