Objective: To determine the efficacy of bilateral uterine artery ligation in the treatment of symptomatic uterine fibroids.
Design: A descriptive study.
Setting: Tertiary care gynecological clinic, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
Sample: Fifty women who had trans-vaginal bilateral uterine artery ligation for the treatment of uterine fibroids between January 2003 and January 2006.
Methods: Pre-operative baseline ultrasonic measurements of uterine and dominant fibroid volumes were carried out and repeated at two, six, and 12 weeks, then three monthly for a period of three years. Severity of menstrual blood loss, changes in pain symptoms and patients' satisfaction were also assessed.
Main Outcome Measures: Changes in uterine and fibroid volumes, hemoglobin values, menstrual pain ratings, and patients' satisfaction ratings.
Results: The mean fibroid volume, mean uterine volume, and mean menstrual pain rating showed statistically significant reductions at six, 12, and 36 months. The mean hemoglobin level and patients' satisfaction rating showed a statistically significant increase after six, 12, and 36 months.
Conclusion: Trans-vaginal bilateral uterine artery ligation is a safe and effective method for the treatment of symptomatic uterine fibroids especially in areas where access to high level medical technology is restricted.
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http://dx.doi.org/10.1080/00016340802632366 | DOI Listing |
Front Physiol
December 2024
Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
During pregnancy, marked changes in vasculature occur. The placenta is developed, and uteroplacental and fetoplacental circulations are established. These processes may be negatively affected by genetic anomalies, maternal environment (i.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
December 2024
Ultrasound Department, Ganzhou Maternal and Child Health Hospital, No. 25, Nankang Road, Zhanggong District, Ganzhou City, Jiangxi Province, 341000, China.
Objective: To study the implementation value of abdominal B-ultrasound combined with cervical cerclage in the prevention and treatment of recurrent late abortion.
Methods: From October 2020 to December 2023, 196 pregnant patients who had a history of late abortions at our institution were chosen. They were divided into groups based on the treatments used.
Am J Reprod Immunol
January 2025
Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Preeclampsia is one of the most severe obstetric complications, yet its pathogenesis remains unclear. Decidual natural killer (dNK) cells, the most abundant immune cells at the maternal-fetal interface, are closely associated with preeclampsia due to abnormalities in their quantity, phenotype, and function. This review summarizes the molecular mechanisms by which dNK cells regulate extravillous trophoblast (EVT) invasion, promote uterine spiral artery remodeling, and maintain immune tolerance.
View Article and Find Full Text PDFOpen Vet J
November 2024
Theriogenology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Background: Senility influences fertility in women and companion animals, especially horses.
Aim: This study aimed to investigate the effect of aging in horses on the daily changes in the dominant follicle (DF) dynamics and hemodynamics, antimüllerian hormone (AMH), enzymes, antioxidants, and ovarian hormones during the estrous cycle.
Methods: Ovaries of old mares ( = 5, age >20 years) and young native mares ( = 6, age <10 years) were scanned during 6 different estrous cycles from March 2022 to August 2023 with Doppler ultrasound.
J Minim Invasive Gynecol
December 2024
Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy; Department of Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Objective: To comparatively evaluate the effectiveness of uterine artery embolization (UAE), focused ultrasound (HIFU), radiofrequency ablation (RFT), and laparoscopic/laparotomic surgery in the conservative treatment of uterine fibroids DATA SOURCES: The research was performed via electronic databases PubMed, EMBASE, and Cochrane Library, using the PRISMA standards.
Methods Of Study Selection: The network included 10 randomized trials between 2000 and 2024 and 1002 randomized subjects.
Tabulation: The Network meta-analysis (NMA) was carried out with subroutine netmeta on R.
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