AI Article Synopsis

  • This text discusses the second reported case of severe postvaccinial encephalitis, a rare complication following smallpox vaccination since it resumed in 2002.
  • Both patients involved showed significant improvement after being treated early with intravenous immunoglobulin.
  • The featured patient received additional treatments, including vaccinia immunoglobulin and corticosteroids, and ultimately achieved full recovery.

Article Abstract

We report the second case of severe postvaccinial encephalitis with acute disseminated encephalomyelitis since smallpox vaccination was reintroduced in 2002. Both affected patients responded dramatically with early intervention of intravenous immunoglobulin. Our patient, who also received concurrent vaccinia immunoglobulin and corticosteroids, demonstrated full recovery.

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http://dx.doi.org/10.1086/596553DOI Listing

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