The fulfillment of their professional responsibilities as necessity, prevent to physicians sometimes to reflect upon medical scientific knowledge validity. In this paper some reflections about it are made considering the importance of integral vision of medicine for the physicians. This knowledge result of scientific development and special application methods. The reflection on medical scientific knowledge validity is different from its historical or ethical valuation. The author point out four dimensions strongly connected on such validity: construct which result of theorical and empirical validity, and consensus validity. The four dimensions are modified for diverse factors.
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