Objective: To assess the results of treatment for a first episode of benign paroxysmal positional vertigo (BPPV) and risk factors for recurrence.
Study Design: Retrospective chart review of 148 BPPV patients at a tertiary care referral centre.
Materials And Methods: The canalith repositioning procedure (CRP) was performed until vertigo and nystagmus were resolved. Using multivariate logistic regression, we estimated the relationship between the rate of BPPV recurrence within 1 year and various risk factors for BPPV.
Results: Among the 145 patients after successful manoeuvre or spontaneous resolution, BPPV recurred in 31 patients (21%) within 1 year. Patients with recurrent BPPV in the posterior semicircular canal required more CRP sessions and a longer period. The rate of BPPV recurrence in patients with endolymphatic hydrops (75%) was significantly higher than in those without (odds ratio 17; 95% confidence interval 2.9-101). Both the first episode of BPPV and recurrent BPPV affected the same ear associated with endolymphatic hydrops in all patients with this complication.
Conclusions: Our data suggest that endolymphatic hydrops is a risk factor for recurrence of BPPV and that prevention of recurrent BPPV is important for control of endolymphatic hydrops.
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J Med Case Rep
January 2025
Centers for Advanced Ent, Woodbridge, VA, US.
Background: Meniere's disease arises when an abnormal fluid accumulation results in heightened pressure within the inner ear or labyrinth. Its symptoms encompass vertigo, tinnitus, hearing loss, and a sensation of fullness in the ear. Various triggers for Meniere's disease are known, from smoking and alcohol consumption to recent viral illnesses, allergies, and anxiety.
View Article and Find Full Text PDFGenome Med
January 2025
Otology & Neurotology Group CTS495, Instituto de Investigación Biosanitario, Ibs.GRANADA, Universidad de Granada, 18071, Granada, Spain.
Background: Familial Meniere's disease (FMD) is a rare polygenic disorder of the inner ear. Mutations in the connexin gene family, which encodes gap junction proteins, can also cause hearing loss, but their role in FMD is largely unknown.
Methods: We retrieved exome sequencing data from 94 individuals in 70 Meniere's disease (MD) families.
Acta Otolaryngol
January 2025
School of Audiology and Speech Language Pathology, Bharati Vidyapeeth (Deemed to be University), Pune, India.
Background: Meniere's disease (MD) affects 0.2% to 0.5% of the global population, with regional variations.
View Article and Find Full Text PDFLaryngoscope
January 2025
Department of Otology and Skull Base Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China.
Objective: Endolymphatic sac tumors (ELSTs), as rare low-grade neoplasms, are primarily treated with surgery. This study analyzes the characteristics of tumor-infiltrating leukocytes (TILs) in ELSTs and their relationships with clinical features to explore the potential for immunotherapy in ELSTs.
Methods: Clinical data and tumor specimens of 10 ELSTs patients who underwent surgery were retrieved.
FASEB J
January 2025
Department of Otolaryngology-Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Meniere's disease (MD) is an inner ear disease characterized by endolymphatic hydrops (EH). Maintaining a regular daily routine is crucial for MD patients. However, the relationship between circadian rhythms and MD remains unclear.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!