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Dermatological dichotomy: Atopic dermatitis or mycosis fungoides?
Asia Pac Allergy
December 2024
Allergy and Clinical Immunology Department, Coimbra University Hospital Centre, Coimbra, Portugal.
Article Synopsis
- Atopic dermatitis (AD) and mycosis fungoides (MF) can be difficult to distinguish because they exhibit similar symptoms like inflamed and itchy skin lesions.
- A case study of a 19-year-old male with a past AD history highlights the diagnostic confusion when he developed atypical eczema-like lesions that required advanced testing to confirm MF after initial misdiagnosis.
- The case underscores the importance of accurate and early diagnosis to differentiate between AD and MF, as MF requires specific treatments, and it encourages further research into shared mechanisms for improved patient care.
Introduction: Lymphocytic esophagitis (LyE) is a rare esophageal disorder of unknown etiology, characterized by dense peripapillary lymphocytes without neutrophils or eosinophils, and spongiosis. Patients typically present with symptoms such as dysphagia or chest pain. Here, we describe a notable case of lymphocytic esophagitis in a patient who presented with food impaction.
View Article and Find Full Text PDFA clinical case of pityriasis lichenoides chronica presenting with palpable purpura after streptococcal infection.
Folia Med (Plovdiv)
June 2024
Sofiamed University Hospital, St Kliment Ohridski University, Sofia, Bulgaria.
Article Synopsis
- Pityriasis lichenoides is a rare inflammatory skin condition characterized by red-brown papules and crusty lesions as they evolve over time.
- A 60-year-old woman developed the chronic form of this condition ten days after suffering from streptococcal pharyngitis, starting with purple spots on her legs and later developing red, scaly patches on other parts of her body.
- After treatment with methylprednisolone and hydroxychloroquine, her skin lesions improved significantly and did not return.
Pityriasis Rubra Pilaris in an Atopic Dermatitis Patient: A Case Report.
Cureus
August 2024
Dermatology, King Abdulaziz Hospital, Makkah, SAU.
Article Synopsis
- - Pityriasis rubra pilaris (PRP) is a rare skin condition characterized by chronic inflammation and scaly patches, affecting mostly the extremities while sparing the trunk.
- - A 43-year-old woman with a history of atopic dermatitis presented with itchy skin lesions, and after thorough examination and biopsy, she was diagnosed with atypical adult PRP (type II).
- - The patient was treated with narrowband UVB phototherapy, leading to complete clearance of skin lesions within two months, and she has remained lesion-free for two years during follow-up.
Single-cell sequencing delineates T-cell clonality and pathogenesis of the parapsoriasis disease group.
J Allergy Clin Immunol
September 2024
Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:
Article Synopsis
- Mycosis fungoides (MF), a type of skin cancer, is often misdiagnosed early on because it resembles conditions like atopic dermatitis (AD), complicating the distinction from parapsoriasis, which can appear in small or large plaques.
- The study used single-cell RNA sequencing to analyze skin samples from patients showing both parapsoriasis and early-stage MF to better understand these diseases.
- Results showed that large-plaque lesions tended to have signs of early-stage MF while small-plaque lesions were more diverse and lacked cancerous characteristics, leading researchers to propose the term "polyclonal parapsoriasis en plaque" for these unique lesions.
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