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Background: Intraoperative neuromonitoring (IONM) is crucial for the safety of scoliosis surgery, providing real-time feedback on the spinal cord and nerve function, primarily through motor-evoked potentials (MEPs). The choice of anesthesia plays a crucial role in influencing the quality and reliability of these neuromonitoring signals. This systematic review evaluates how different anesthetic techniques-total intravenous anesthesia (TIVA), volatile anesthetics, and regional anesthesia approaches such as Erector Spinae Plane Block (ESPB), spinal, and epidural anesthesia-affect IONM during scoliosis surgery.

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Introduction Endoscopic retrograde cholangiopancreatography (ERCP) requires effective sedation for patient comfort and procedural success. This study compares propofol-dexmedetomidine (group DP) and propofol-ketamine (group KP) for anesthetic management during ERCP. Methods This randomized, double-blinded study enrolled 50 patients (aged 18-60 years) scheduled for ERCP at Dr.

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Objectives: The aim of the present study was to evaluate the differences in intraoperative nociception, incision size and operative time between midline (OVE) and flank ovariectomy (OVE) in feral or stray cats.

Methods: Two groups of animals, the OVE group (n = 19) and the OVE group (n = 19), were evaluated at six intraoperative time points. Cats assigned to both groups were premedicated with dexmedetomidine (20 μg/kg IM) and methadone (0.

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Dexmedetomidine suppresses glucose-stimulated insulin secretion in pancreatic β-cells.

FEBS Open Bio

December 2024

Department of Cell Physiology, Institute of Biomedical Science, Kansai Medical University, Hirakata, Osaka, Japan.

Proper glycemic control is crucial for patient management in critical care, including perioperative care, and can influence patient prognosis. Blood glucose concentration determines insulin secretion and sensitivity and affects the intricate balance between the glucose metabolism. Human and other animal studies have demonstrated that perioperative drugs, including volatile anesthetics and intravenous anesthetics, affect glucose-stimulated insulin secretion (GSIS).

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Background: Foreign body (coins, magnets, button batteries, and metallic foreign bodies) ingestion is common and causes significant morbidity and mortality in children aged six months to three years. Endoscopic removal of swallowed foreign substances is widely accepted, but sedation and general anesthesia may be required to alleviate pain and anxiety during the procedure. Dexmedetomidine is used as a sedative, hypnotic, anxiolytic, and analgesic.

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