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A case series of Mediterranean spotted fever and murine typhus with neurological manifestations.
J Vector Borne Dis
July 2024
Infectious Diseases Department, Hedi Chaker University Hospital, University of Sfax, Tunisia.
Article Synopsis
- The study investigated the characteristics of central nervous system rickettsial infections in patients hospitalized with rickettsiosis over 25 years in Tunisia.
- Out of 440 patients, 47 had neurological symptoms, showing that skin rashes and eschars were less common in these cases, along with a higher rate of complications and mortality.
- The findings suggest that typical symptoms and lab results were less pronounced in central nervous system cases, indicating a more severe prognosis.
The case of Mediterranean spotted fever of the traveler returned from Zambia.
Ticks Tick Borne Dis
July 2024
Sapporo City General Hospital Department of Infectious Diseases, 13-1-1, Kita-11-jonishi, Chuo-ku, Sapporo 060-8604, Japan.
Article Synopsis
- * The diagnosis was confirmed using Polymerase Chain Reaction assays, and the patient recovered after a 10-day treatment with doxycycline.
- * This case is significant because, although MSF has been noted in sub-Saharan Africa, it hasn't been previously reported in Zambia, indicating a potential health risk in urban regions there.
A Case of Mediterranean Spotted Fever with Cerebral Infarction.
Vector Borne Zoonotic Dis
July 2024
Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, Turkey.
Serological and molecular epidemiological investigation of Mediterranean spotted fever in Yunnan Province, China.
Infect Genet Evol
March 2024
The Institute for Tropical Medicine, School of Basic Medical Sciences, Kunming Medical University, Kunming 650500, China; Yunnan Provincial Key Laboratory of Public Health and Biosafety, School of Public Health, Kunming Medical University, Kunming 650500, China; Yunnan Province Key Laboratory of Children's Major Diseases Research, The Affiliated Children's Hospital, Kunming, Kunming Medical University, Kunming 650030, China; Yunnan Demonstration Base of International Science and Technology Cooperation for Tropical Diseases, Kunming 650500, China. Electronic address:
Article Synopsis
- The study investigates the prevalence of Mediterranean spotted fever (MSF), caused by the bacterium Rickettsia conorii, in Yunnan Province, China, due to limited previous research and its health risks.
- Researchers collected 5,358 blood samples from healthy individuals using various testing methods, finding a low prevalence of MSF, with only one positive PCR result for R. conorii.
- The results indicate a geographical and climatic influence on MSF prevalence in Yunnan, highlighting the need for more research to improve understanding and intervention strategies for this tick-borne disease.
Rickettsia conorii subsp. israelensis infection in a pediatric patient presenting skin rash and abdominal pain: a case report from Southeast Iran.
BMC Infect Dis
January 2024
National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Kabudar Ahang, Akanlu, Hamadan, Iran.
Article Synopsis
- The Iranian healthcare system does not adequately recognize Mediterranean spotted fever (MSF) as a common illness, especially in children, highlighting a need for increased awareness.
- A six-year-old boy in southeast Iran exhibited symptoms such as fever, abdominal pain, and skin rashes, and was diagnosed with a rickettsial infection caused by Rickettsia conorii subsp. israelensis, which was confirmed through clinical tests.
- Early symptoms of MSF can include rashes and abdominal pain, and diagnostic methods such as indirect fluorescent antibody (IFA) tests and real-time PCR are essential for accurate identification of the disease.
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