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Monitoring SARS-CoV-2 variants with complementary surveillance systems: risk evaluation of the Omicron JN.1 variant in France, August 2023 to January 2024.
Euro Surveill
January 2025
National Reference Center for Respiratory Viruses, Hospices Civils de Lyon, CIRI, INSERM U1111, University Claude Bernard Lyon 1, Lyon, France.
BackgroundEarly detection and characterisation of SARS-CoV-2 variants have been and continue to be essential for assessing their public health impact. In August 2023, Santé publique France implemented enhanced surveillance for BA.2.
View Article and Find Full Text PDFExploring Peripheral and Cardiac Immune Responses in a Pneumosepsis Mouse Model with Group A Streptococcus.
Am J Respir Cell Mol Biol
January 2025
Rostock University Medical Center, Institute of Medical Microbiology, Virology and Hygiene, Rostock, Germany.
(Group A Streptococcus, GAS) is a human pathogen that causes local and systemic infections of the skin and mucous membranes. However, GAS is also found asymptomatically in the nasopharynx of infants. GAS infections, including pharyngitis and invasive pneumosepsis, pose significant public health concerns.
View Article and Find Full Text PDFdetectCilia: An R Package for Automated Detection and Length Measurement of Primary Cilia.
Bioinform Biol Insights
October 2024
Institute for Visual and Analytic Computing, University of Rostock, Rostock, Germany.
Background And Objective: The primary cilium is a small protrusion found on most mammalian cells. It acts as a cellular antenna, being involved in various cell signaling pathways. The length of the primary cilium affects its function.
View Article and Find Full Text PDFRepurposing weather modification for cloud research showcased by ice crystal growth.
PNAS Nexus
September 2024
Department of Environmental Systems Science, Institute for Atmospheric and Climate Science, ETH Zurich, Zurich 8092, Switzerland.
The representation of cloud processes in models is one of the largest sources of uncertainty in weather forecast and climate projections. While laboratory settings offer controlled conditions for studying cloud processes, they cannot reproduce the full range of conditions and interactions present in natural cloud systems. To bridge this gap, here we leverage weather modification, specifically glaciogenic cloud seeding, to investigate ice growth rates within natural clouds.
View Article and Find Full Text PDFChiSCAT: Unsupervised Learning of Recurrent Cellular Micromotion Patterns from a Chaotic Speckle Pattern.
Nano Lett
October 2024
Institute of Physics, University of Rostock, 18059 Rostock, Germany.
There is considerable evidence that action potentials are accompanied by "intrinsic optical signals", such as a nanometer-scale motion of the cell membrane. Here we present ChiSCAT, a technically simple imaging scheme that detects such signals with interferometric sensitivity. ChiSCAT combines illumination by a aotic speckle pattern and interferometric scattering microscopy () to sensitively detect motion in any direction.
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