Background: There are few comprehensive estimates of the cost of psoriasis in the United States.
Objective: We sought to quantify the incremental direct medical and indirect work loss costs associated with psoriasis.
Methods: A de-identified claims database from 31 self-insured employers during the period 1998 to 2005 was used. Patients with at least two psoriasis diagnosis claims (N = 12,280) were compared with 3 control subjects (matched on year of birth and sex) without psoriasis. Multivariate two-part regression analysis was used to isolate the incremental cost of psoriasis by controlling for comorbidities and other confounding factors.
Results: After multivariate adjustment, the incremental direct and indirect costs of psoriasis were approximately $900 and $600 (P < .001) per patient per year, respectively.
Limitations: The database used in this study does not contain information on patient out-of-pocket costs or loss of productivity costs at work.
Conclusion: The incremental cost of psoriasis is approximately $1500 per patient per year, with work loss costs accounting for 40% of the cost burden.
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http://dx.doi.org/10.1016/j.jaad.2008.06.043 | DOI Listing |
PLoS One
January 2025
School of Behavioral Sciences, The Academic College of Tel Aviv-Yafo, Tel Aviv, Israel.
Background: Occupational burnout, resulting from long-term exposure to work-related stressors, is a significant risk factor for both physical and mental health of employees. Most research on burnout focuses on routine situations, with less attention given to its causes and manifestations during prolonged national crises such as war. According to the Conservation of Resources theory, wartime conditions are associated with a loss of resources, leading to accelerated burnout.
View Article and Find Full Text PDFChemSusChem
January 2025
Dipartimento di Scienze Biologiche, Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale delle Scienze, Ed. 17, 90128, Palermo, Italia.
Valorization of carbohydrate-rich biomass by conversion into industrially relevant products is at the forefront of research in sustainable chemistry. In this work, we studied the inulin conversion into 5-hydroxymethylfurfural, in deep eutectic solvents, in the presence of acidic task-specific ionic liquids as catalysts. We employed aliphatic and aromatic ionic liquids as catalysts, and choline chloride-based deep eutectic solvents bearing glycols or carboxylic acids, as solvents.
View Article and Find Full Text PDFStat Med
February 2025
School of Mathematical Science, Queensland University of Technology, Brisbane, Australia.
To date, there have not been any population-based cancer studies quantifying geographical patterns of the loss in life expectancy (LLE) and crude probability of death due to cancer ( ). These absolute measures of survival are complementary to the more typically used relative measures of excess mortality and relative survival, and, together, they provide a fuller understanding of geographical disparities in survival outcomes for cancer patients. We propose using a spatially flexible parametric relative survival model in the Bayesian framework, which allows for the inclusion of spatial effects in hazard-level model components.
View Article and Find Full Text PDFSports Med
January 2025
School of Behavioural and Health Sciences, Australian Catholic University, Melbourne, VIC, Australia.
Following anterior cruciate ligament (ACL) injury, quadriceps muscle atrophy persists despite rehabilitation, leading to loss of lower limb strength, osteoarthritis, poor knee joint health and reduced quality of life. However, the molecular mechanisms responsible for these deficits in hypertrophic adaptations within the quadriceps muscle following ACL injury and reconstruction are poorly understood. While resistance exercise training stimulates skeletal muscle hypertrophy, attenuation of these hypertrophic pathways can hinder rehabilitation following ACL injury and reconstruction, and ultimately lead to skeletal muscle atrophy that persists beyond ACL reconstruction, similar to disuse atrophy.
View Article and Find Full Text PDFAppl Environ Microbiol
January 2025
Department of Microbiology & Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
is an opportunistic pathogen with four subspecies: (FNN), (FNV), (FNP), and (FNA), each with distinct disease potentials. Research on fusobacterial pathogenesis has mainly focused on the model strain ATCC 23726 from FNN. However, this narrow focus may overlook significant behaviors of other FNN strains and those from other subspecies, given the genetic and phenotypic diversity within .
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