Background: There are few comprehensive estimates of the cost of psoriasis in the United States.

Objective: We sought to quantify the incremental direct medical and indirect work loss costs associated with psoriasis.

Methods: A de-identified claims database from 31 self-insured employers during the period 1998 to 2005 was used. Patients with at least two psoriasis diagnosis claims (N = 12,280) were compared with 3 control subjects (matched on year of birth and sex) without psoriasis. Multivariate two-part regression analysis was used to isolate the incremental cost of psoriasis by controlling for comorbidities and other confounding factors.

Results: After multivariate adjustment, the incremental direct and indirect costs of psoriasis were approximately $900 and $600 (P < .001) per patient per year, respectively.

Limitations: The database used in this study does not contain information on patient out-of-pocket costs or loss of productivity costs at work.

Conclusion: The incremental cost of psoriasis is approximately $1500 per patient per year, with work loss costs accounting for 40% of the cost burden.

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http://dx.doi.org/10.1016/j.jaad.2008.06.043DOI Listing

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