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First autochthonous case of Opisthorchis felineus in Austria.
Parasit Vectors
January 2025
Department for Companion Animals and Horses, University Hospital for Small Animals, University of Veterinary Medicine Vienna, Vienna, Austria.
Background: Opisthorchis felineus is a feline pathogen with zoonotic potential that can be a causative agent of human opisthorchiasis and cholangiocarcinoma. In Europe, O. felineus is particularly endemic in Eastern European countries, while this parasite has also been sporadically detected in Germany, Italy and northern Poland.
View Article and Find Full Text PDF3D synergistic tumor-liver analysis further improves the efficacy prediction in hepatocellular carcinoma: a multi-center study.
BMC Cancer
January 2025
Department of Radiology, Zhuhai Clinical Medical College of Jinan University (Zhuhai People's Hospital, The Affiliated Hospital of Beijing Institute of Technology), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China.
Background: Besides tumorous information, synergistic liver parenchyma assessments may provide additional insights into the prognosis of hepatocellular carcinoma (HCC). This study aimed to investigate whether 3D synergistic tumor-liver analysis could improve the prediction accuracy for HCC prognosis.
Methods: A total of 422 HCC patients from six centers were included.
Explainable machine learning models for identifying mild cognitive impairment in older patients with chronic pain.
BMC Nurs
January 2025
Department of Pain Medicine, the 1st affiliated hospital, Jiangxi Medical College, Nanchang University, 17 Yongwai Street, Nanchang, China.
Background: Mild cognitive impairment (MCI) is prevalent in older adults with chronic pain, making early detection crucial for dementia prevention and healthy aging. This study aimed to determine MCI risk factors in older patients with chronic pain and to develop 9 machine learning models to identify MCI risk.
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Functional genomic imaging (FGI), a virtual tool for visualization of functional gene expression modules in heterogeneous tumor samples.
Biol Direct
January 2025
Shanghai LIDE Biotech Co., Ltd., Shanghai, 201203, China.
Advances in sequencing technologies are reshaping clinical diagnostics, prompting the development of new software tools to decipher big data. To this end, we developed functional genomic imaging (FGI), a visualization tool designed to assist clinicians in interpreting RNA-Seq results from patient samples. FGI uses weighted gene co-expression network analysis (WGCNA), followed by a modified Phenograph clustering algorithm to identify co-expression gene clusters.
View Article and Find Full Text PDFCollaborative management of severe periodontal-endodontic lesion with intense lip sucking: a case report.
BMC Oral Health
January 2025
Qingdao Municipal Hospital, Shandong, 266071, China.
Background: Lip behaviors can lead to maxillofacial developmental disorders such as anterior open bite, posterior crossbite, increased overjet, and a higher risk of developing a Class II malocclusion. However, lip-sucking, a behavior often underreported and overlooked, may adversely affect the periodontal health of permanent teeth in adolescents under extreme conditions if not promptly identified and managed.
Case Presentation: We report a unique case of an 11-year-old boy with a severe periodontal-endodontic lesion on tooth 32, caused by prolonged, high-frequency, and high-intensity lip sucking.
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