[Leptin, insulin, IGF-1 and bone mass in a group of sedentary adolescent girls].

J Med Liban

Laboratoire de physiologie et de biomécanique de la performance motrice, Université de Balamand, Al Koura, Liban.

Published: January 2009

Aim Of The Study: To investigate the relationships between serum leptin, IGF-1, insulin and bone mineral content and density in a group of Lebanese sedentary adolescent girls.

Methods And Results: Twenty Lebanese sedentary adolescent girls participated in our study. Total body bone mineral content and density were measured by dual-energy X-ray absorptiometry (DEXA). In parallel, fasting leptin, IGF-1 and insulin concentrations were also measured. Serum leptin, IGF-1 and insulin concentrations were not associated with total body bone mineral content (BMC), total body bone mineral density (BMD) or pelvis BMD.

Conclusion: Serum leptin, IGF-1 and insulin concentrations are not positive predictors of total body bone mineral content or density in this study group.

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