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The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review). | LitMetric
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The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review).

Jennifer Greaves Gerald R Prescott Oforiwa A Gorleku Luke H Chamberlain

Mol Membr Biol

The Centre for Integrative Physiology, School of Biomedical Sciences, University of Edinburgh, Edinburgh, UK.

Published: January 2009

The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.

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http://dx.doi.org/10.1080/09687680802620351DOI Listing

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