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Sex differences between postmenopausal women and similar-age men in response to orthostatic stress following 2 wk of bed rest.
J Appl Physiol (1985)
January 2025
Schlegel-UW Research Institute for Aging, Waterloo, Ontario, Canada.
Reduced orthostatic tolerance is common following periods of bed rest that are associated with illness or surgery, putting individuals at higher risk for syncope and falls following hospitalization. Following menopause, mechanisms of female cardiovascular regulation change, which may be associated with sex-specific responses to orthostatic stress following bed rest. The purpose of our experiment was to investigate sex differences between healthy postmenopausal women and similar-age men (age: 55-65 yr) for their orthostatic tolerance and cerebrovascular responses to standing following bed rest.
View Article and Find Full Text PDFAbnormal Upper Gastrointestinal Motility Reduces the Efficacy of Colectomy for Colonic Inertia: A Systematic Review and Meta-analysis.
J Clin Gastroenterol
February 2025
Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston.
Article Synopsis
- This systematic review evaluated how upper gastrointestinal (UGI) dysmotility affects outcomes in patients with colonic inertia (CI) undergoing surgery.
- It found that patients with UGI dysmotility were more likely to experience recurrence of constipation after surgery and had poorer improvements in quality of life compared to those without UGI issues.
- The review suggests routine evaluation of UGI function before surgery for CI, as many patients with UGI dysmotility may go undiagnosed.
Interplay of Cardiometabolic Syndrome and Biliary Tract Cancer: A Comprehensive Analysis with Gender-Specific Insights.
Cancers (Basel)
October 2024
Gastroenterology Unit, National Institute of Gastroenterology IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.
BTC overall incidence is globally increasing. CCA, including its subtypes, is a form of BTC. MetS, obesity, MASLD, and diabetes are all linked to CCA in interconnected ways.
View Article and Find Full Text PDFUnraveling of Molecular Mechanisms of Cognitive Frailty in Chronic Kidney Disease: How Exercise Makes a Difference.
J Clin Med
September 2024
Sports Medicine Laboratory, School of Physical Education & Sport Science, Aristotle University, 57 001 Thessaloniki, Greece.
As our population ages, the medical challenges it faces become increasingly acute, with chronic kidney disease (CKD) becoming more prevalent among older adults. Frailty is alarmingly more common in CKD patients than in the general populace, putting the elderly at high risk of both physical and cognitive decline. CKD not only accelerates physical deterioration, but also heightens vascular dysfunction, calcification, arterial rigidity, systemic inflammation, oxidative stress, and cognitive impairment.
View Article and Find Full Text PDFPutting it into words: Emotion vocabulary, emotion differentiation, and depression among adolescents.
Emotion
February 2025
Department of Psychology, University of Rochester.
Emotion differentiation (ED; the ability to distinguish discrete internal emotion states) may reflect or benefit from knowledge of linguistic labels. The present study uses natural language processing to examine how emotion vocabulary (EV; diversity of unique emotion terms within active vocabulary) relates to ED and depression in an adolescent sample. We tested two competing preregistered (https://osf.
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