In this descriptive prospective study, 269 African American, Hispanic, and Caucasian women from rural prenatal clinics were interviewed once between 16 and 28 weeks' gestation. Associations between biopsychosocial risk factors and preterm birth (PTB) were examined. African American women with spontaneous PTB were more likely to be older, and to have higher Bowman Gray Risk Index scores and hypertensive diseases of pregnancy than African American women who did not have a spontaneous PTB. There were significant differences in bacterial vaginosis, hypertensive diseases of pregnancy, smoking, social support from others, and self-esteem among the three racial groups. In the total sample after adjustment for sociodemographic and biopsychosocial factors, women with spontaneous PTB were three times more likely to be African American, to have oligohydramnios, hypertensive diseases of pregnancy, and had higher Bowman Gray Risk Index scores than the total sample of women without spontaneous PTB. Understanding the risks associated with spontaneous PTBs that are unique to African American women and why biopsychosocial risk factors vary by racial/ethnic group may lead to tailored interventions.
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http://dx.doi.org/10.1016/j.jmwh.2008.08.009 | DOI Listing |
JMIR Form Res
January 2025
Graduate School of Public Health Policy, City University of New York, New York, NY, United States.
Background: Childhood obesity prevalence remains high, especially in racial and ethnic minority populations with low incomes. This epidemic is attributed to various dietary behaviors, including increased consumption of energy-dense foods and sugary beverages and decreased intake of fruits and vegetables. Interactive, technology-based approaches are emerging as promising tools to support health behavior changes.
View Article and Find Full Text PDFPediatr Cardiol
January 2025
Division of Cardiology, Children's Healthcare of Atlanta, Emory University School of Medicine, 2970 Brandywine Rd, Suite 125, Atlanta, GA, 30341, USA.
Evaluate patent ductus arteriosus (PDA) morphology changes in the preterm neonate undergoing transcatheter PDA closure (TCPC). We propose the type F ductus is associated with lower corrected gestational age (CGA) and improved TCPC outcomes. Retrospective review of premature neonates undergoing TCPC at a large volume institution from November 2020 to November 2023.
View Article and Find Full Text PDFGenet Epidemiol
January 2025
Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester, UK.
Transcriptome-wide association studies (TWAS) investigate the links between genetically regulated gene expression and complex traits. TWAS involves imputing gene expression using expression quantitative trait loci (eQTL) as predictors and testing the association between the imputed expression and the trait. The effectiveness of TWAS depends on the accuracy of these imputation models, which require genotype and gene expression data from the same samples.
View Article and Find Full Text PDFPhysiol Genomics
January 2025
Section of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
Aspirin (ASA) is a proven chemoprotective agent for colorectal cancer (CRC), though inter-individual responses and cellular mechanisms are not well characterized. Human organoids are ideal to study treatment responses across individuals. Here, colonic organoids from African-Americans (AA) and European-Americans (EA)were used to profile genomic and cellular ASA responses.
View Article and Find Full Text PDFCureus
December 2024
Hematology and Medical Oncology, East Carolina University (ECU) Health Medical Center/Brody School of Medicine, Greenville, USA.
Primary cutaneous B-cell lymphoma (PCBCL) has three subtypes, among those, the leg type variant is the rarest with the highest rates of relapse and recurrence making it an intriguing focus for researchers. Nevertheless, prior to framing a diagnosis solely based on the lesion's location, it is prudent to reconsider whether it is genuinely a primary cutaneous B-cell lymphoma (PCBCL) or if it aligns more closely with the more prevalent lymphoma variants such as diffuse large B-cell lymphoma (DLBCL) with cutaneous involvement. We are reporting a case of an 85-year-old African American lady, who presented with unilateral left leg DLBCL with cutaneous involvement.
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