Ocular tuberculosis occurs rarely and causes many diagnostic difficulties. The aim of this paper is to provide an analysis of diagnostic problems of ocular changes as a consequence of Mycobacterium tuberculosis infection in children. Between 2006 and 2007 there were 7 children at the age 8 to 16 years old, treated in Ophthalmic Department. The infection or contact with Mycobacterium tuberculosis was diagnosed through the range of examination. Diagnosis of tuberculosis included chest radiography, computed tomography of lungs, tuberculin skin test and bronchoscopy. Gastric and bronchial aspirates were used for bacterial and genetic investigations. In eyes with ocular tuberculosis there were various intraocular changes. The most common clinical presentation occurred by intermediate uveitis, posterior uveitis and optic neuritis. 5 children were treated with antituberculous drugs, 2 children were observed without treatment. Examination and treatment of ocular tuberculosis required cooperation with specialists of pulmonary diseases.
Download full-text PDF |
Source |
---|
Eye (Lond)
January 2025
Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Objective: To describe clinical features, treatment strategies and visual acuity changes of eyes with uveitic macular oedema (UMO) in ocular tuberculosis (OTB) patients from a non-TB-endemic country.
Methods: This retrospective study was conducted using a 10-year period registry of OTB patients diagnosed in Erasmus MC, Rotterdam. Longitudinal analysis of visual acuity trajectory in eyes with and without UMO was performed using linear mixed effect model.
BMC Ophthalmol
January 2025
Department of Tuberculosis, New District Branch of Northern Jiangsu People's Hospital of Jiangsu Province, Yangzhou, 225001, Jiangsu Province, China.
Background: This study aims to detect Mycobacterium tuberculosis complex (MTBC) DNA in intraocular fluid from clinically suspected tuberculous uveitis patients using multiplex polymerase chain reaction (PCR) and investigate the diagnostic utility of multiplex PCR for tuberculous uveitis.
Methods: Primers targeting three specific genes (MPB64, CYP141, and IS6110) within the MTBC genome were designed. Multiplex PCR was conducted using DNA from the H37Rv strain as well as DNA extracted from fluids of confirmed tuberculosis patients to assess primer specificity and method feasibility.
Zhonghua Yan Ke Za Zhi
January 2025
Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin300052, China.
Ocul Immunol Inflamm
December 2024
Beijing Ophthalmology & Visual Science Key Lab, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Purpose: Ocular tuberculosis (OTB), an extrapulmonary manifestation of tuberculosis (TB), significantly impacts vision acuity and presents challenges in diagnosis and treatment. With ongoing research efforts, new insights into its pathogenesis and treatment have emerged. This study employed bibliometric methods to investigate key research areas and emerging trends, aiming to provide a comprehensive overview of the field.
View Article and Find Full Text PDFJ Maxillofac Oral Surg
December 2024
Department of Oral & Maxillofacial Surgery, Army Dental Centre (Research & Referral), Cantt-10, Delhi, India.
Tuberculosis (TB) manifests in various forms, including extrapulmonary tuberculosis (EPTB), which poses diagnostic dilemmas due to its wide-ranging clinical presentations. When TB affects the bones of the hands and feet, it can present a diagnostic labyrinth for clinicians. In such cases, the differential diagnosis may include Jungling's bone disease, adding complexity to the diagnostic process.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!