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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Brain Institute of Rio Grande do Sul - Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Background: Although cognitive decline is a trait related to aging, some individuals are resilient to the aging process, defined as SuperAgers. Studying the neural underpinnings of SuperAgers may improve the understanding of AD pathology. In this study, our aim was to analyze amyloid and neurodegeneration imaging biomarkers in SuperAgers.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Alzheimer's Disease Neuroimaging Initiative, http://adni.loni.usc.edu/, CA, USA.
Background: Amyloid and tau pathologies are the hallmarks of Alzheimer's disease (AD). Previous research indicated notable connections between financial capacity and AD biomarkers. Here, we aimed to understand whether financial capacity is affected by the cerebral accumulation of tau and amyloid.
View Article and Find Full Text PDFTechnology and Dementia Preconference.
Alzheimers Dement
December 2024
Albert Einstein College of Medicine, Bronx, NY, USA.
Background: Alzheimer's disease (AD) is a heterogeneous disease with different clinical phenotypes and pathophysiological subtypes. Identifying cognitive/functional subtypes in AD could elucidate the diverse clinical progression patterns. The Cognitive Function Index (CFI), a 15-item questionnaire completed by participants and study partners, captures aspects of cognitive and functional decline.
View Article and Find Full Text PDFTechnology and Dementia Preconference.
Alzheimers Dement
December 2024
Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Background: The National Institutes of Health Toolbox for Assessment of Neurological and Behavioral Function (NIHTB) was developed to address the need for a brief yet comprehensive instrument to facilitate more uniform assessment in large-scale research studies. Here, we investigated whether the cognitive measures of the NIHTB detect cognitive decline in biomarker-confirmed Alzheimer's disease (AD).
Method: We used data from N = 178 participants (age 76.
Technology and Dementia Preconference.
Alzheimers Dement
December 2024
Research Program on Cognition and Neuromodulation-Based Interventions, University of Michigan, Ann Arbor, MI, USA.
Background: The computerized NIH Toolbox Cognition Battery (NIHTB-CB) was designed to assess cognitive functioning across the lifespan. Previous studies demonstrated that NIHTB-CB measures discriminate between healthy controls (HCs), individuals with amnestic mild cognitive impairment (aMCI), and individuals with dementia of the Alzheimer's type (DAT). Scores on NIHTB-CB tasks also correspond with performance on well-validated neuropsychological measures of the same cognitive domains.
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