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Since current microbiology methods are not suitable to detect Clostridium perfringens in formalin-fixed, paraffin-embedded tissue samples, we developed a PCR assay to detect toxin-encoding genes and the 16S rRNA gene of C. perfringens. We successfully detected and genotyped C. perfringens in tissue sections from two autopsy cases.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650962PMC
http://dx.doi.org/10.1128/JCM.01324-08DOI Listing

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