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Giant proteins: sensing tension with titin kinase. | LitMetric

Giant proteins: sensing tension with titin kinase.

Curr Biol

Astbury Centre for Structural Molecular Biology, Institute for Molecular and Cellular Biology, Leeds University, Leeds, UK.

Published: December 2008

Recent studies at the single-molecule level show how signaling from the giant protein titin can be triggered by direct mechanical activation of its kinase domain.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2008.10.035DOI Listing

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