An amplitude-sensitive technique associated with a heterodyne interferometer for detecting small differential phase is reported. The excess noise with the amplitude-sensitive technique is reduced by optical subtraction instead of electronic subtraction. The differential phase introduced by the orthogonally polarized laser beams is converted to the amplitudes of two heterodyne interferometric signals, which presents amplitude and phase quadrature simultaneously. Thus the excess noise power and quantum noise power are both differential phase dependent. The advantages of differential and additive operations by optical technique and the real time differential phase determination without phase lock in are demonstrated experimentally. The theoretical signal-to-noise ratio (SNR) and minimum detectable differential phase are derived, which takes quantum noise and excess noise into consideration. The experimental results demonstrated the resolutions of differential phase detection closes to 10(-6) rad/square root(Hz) (10(-13) m/square root(Hz)) level over 100 kHz bandwidth and at 10(-8) rad/square root(Hz) (10(-15) m/square root(Hz)) level over 125 MHz bandwidth, respectively, under 2.5 mW incident power.
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http://dx.doi.org/10.1364/ao.47.006860 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Alopecia areata (AA) is a prevalent autoimmune condition that causes sudden hair loss and poses significant psychological challenges to affected individuals. Current treatments, including corticosteroids and Janus kinase inhibitors, fail to provide long-term efficacy due to adverse effects and relapse after cessation. This study introduces a nanoparticle (NP) system that codeliver diphenylcyclopropenone (DPCP) and rapamycin (RAPA) prodrugs to induce immune tolerance and promote hair regeneration.
View Article and Find Full Text PDFHomodyne interferometers (HIs) utilize differential signaling to reduce common-mode noise and enhance measurement stability. However, their potential to improve measurement accuracy has not been thoroughly investigated. To address this gap, we reveal two unrecognized mechanisms enabled by differential-output signal (DS): self-compensation for odd-order periodic nonlinear error (PNE) and mitigation of PNE caused by ghost reflections.
View Article and Find Full Text PDFFourier ptychographic microscopy (FPM) can provide high-throughput imaging by computationally combining low-resolution images at different spatial frequencies within the Fourier domain. The core algorithm for FPM reconstruction draws upon phase retrieval techniques, including methods such as the ptychographic iterative engine (PIE), regularized PIE (rPIE), and embedded pupil function FPM (EPRY-FPM). The calibration of the physical setup plays a crucial role in the quality of the reconstructed high space-bandwidth product (SPB) image.
View Article and Find Full Text PDFWe present a non-interferometric technique for quantitative phase imaging (QPI) that is cost-effective, easily integrated into standard microscopes, and capable of wide-field imaging with noncoherent light. Our method measures the phase gradient through optical differentiation using spatially variable amplitude filters, accommodating a range of transmission functions, including commercially available variable neutral-density filters. This flexibility is made possible by a general relationship we derive.
View Article and Find Full Text PDFSci Rep
January 2025
I-Form Advanced Manufacturing Research Centre, Dublin City University, Dublin, Ireland.
In the realm of materials science and engineering, the pursuit of advanced materials with tailored properties has been a driving goal behind technological progress. Scientific interest in laser powder bed fusion (L-PBF) fabricated NiTi alloy has in recent times seen an upsurge of activity. In this study, we investigate the impact of varying volume energy density (VED) during L-PBF on the microstructure and corrosion behaviour of NiTi alloys in both scan (XY) and built (XZ) planes.
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