Transition of the chronically ill youth with hemoglobinopathy to adult health care: an integrative review of the literature.

With the advent of innovative technologies and medical advances, more than a half million chronically ill youth (CIY) cross the threshold into adulthood yearly. Successful transition of the CIY with hemoglobinopathy (e.g., sickle cell, thalassemia) from pediatrics to adult care continues to be an inconsistent process. The purpose of undertaking a comprehensive empirical review was to synthesize the transition literature focusing on CIY with hemoglobinopathy and clinical recommendations. Among 17 studies critically reviewed and summarized, five studies focused on the CIY with hemoglobinopathy, and the remainder on youth with other chronic conditions. Further research on transition, especially for CIY with hemoglobinopathy, is needed.