Based on a two-year household survey data, the yield gap of winter wheat in Quzhou County of Hebei Province, China in 2003-2004 was studied through comparative performance analysis (CPA). The results showed that there was a greater yield gap (from 4.2 to 7.9 t x hm(-2)) between field blocks, with a variation coefficient of 0.14. Through stepwise forward linear multiple regression, it was found that the yield model with 8 selected variables could explain 63% variability of winter wheat yield. Among the variables selected, soil salinity, soil fertility, and irrigation water quality were the most important limiting factors, accounting for 52% of the total yield gap. Crop variety was another important limiting factor, accounting for 14%; while planting date, fertilizer type, disease and pest, and water press accounted for 7%, 14%, 10%, and 3%, respectively. Therefore, besides soil and climate conditions, management practices occupied the majority of yield variability in Quzhou County, suggesting that the yield gap could be reduced significantly through optimum field management.
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Am J Hum Genet
January 2025
UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA, USA. Electronic address:
More than 50% of families with suspected rare monogenic diseases remain unsolved after whole-genome analysis by short-read sequencing (SRS). Long-read sequencing (LRS) could help bridge this diagnostic gap by capturing variants inaccessible to SRS, facilitating long-range mapping and phasing and providing haplotype-resolved methylation profiling. To evaluate LRS's additional diagnostic yield, we sequenced a rare-disease cohort of 98 samples from 41 families, using nanopore sequencing, achieving per sample ∼36× average coverage and 32-kb read N50 from a single flow cell.
View Article and Find Full Text PDFJ Environ Manage
January 2025
Department of Civil, Environmental and Architectural Engineering, University of Padova, Via Marzolo 9, 35131, Padova, Italy.
The materials removed in the oil separation units of wastewater treatment plants can be referred to as fat, oil and grease (FOG) waste. FOG waste accumulation in treatment plants can cause clogging of pipes, production of excessive scums and foams, and negatively affect air/liquid oxygen transfer. While conventional disposal routes of this material can be limited by its water and organic content, FOG can represent a source of bio-energy other than bio-diesel production.
View Article and Find Full Text PDFExpert Opin Drug Discov
January 2025
Department of Radiology, Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY, USA.
Introduction: Technological advancements in virtual screening (VS) have rapidly accelerated its application in drug discovery, as reflected by the exponential growth in VS-related publications. However, a significant gap remains between the volume of computational predictions and their experimental validation. This discrepancy has led to a rise in the number of unverified 'claimed' hits which impedes the drug discovery efforts.
View Article and Find Full Text PDFNutrients
January 2025
School of Psychology, University of Sheffield, Sheffield S10 2TN, UK.
Background: The average fibre consumption of 4-10-year-old children in the UK is 14.6 g per day, with only 14% of these children reaching the 20 g recommended by the SACN (UK Scientific Advisory Committee on Nutrition), and this 'fibre gap' may be most pronounced in communities with the lowest socioeconomic status. School breakfast clubs target children from disadvantaged communities, but their provision may favour lower-fibre foods, due to perceptions that children will reject higher-fibre foods.
View Article and Find Full Text PDFMolecules
January 2025
Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Photothermal reactions, involving both photochemical and thermal reaction steps, are the most abundant sequences in photochemistry. The derivation of their rate laws is standardized, but the integration of these rate laws has not yet been achieved. Indeed, the field still lacks integrated rate laws for the description of these reactions' behavior and/or identification of their reaction order.
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