Skin infections are more frequent in immunodeficient patients, seniors and infants than in healthy individuals with an intact immune system. The severity of infections ranges from localized, self-limiting cutaneous infections to widespread necrosis of the skin, muscle, and fascia. The most frequent infections of the skin and mucous membranes are caused by bacterial and viral infectious agents. Fungal infection are also important especially in immunocompromised patients. In particular, viruses play an important and increasing role in the development of several tumors including HPV-associated cervical, anal and penile cancer or HHV-8-induced Kaposi sarcoma.
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