We herein describe a new technique to improve the ultrasonic imaging of nonobstructed stone-bearing kidneys. Mannitol-induced diuresis opens up the collapsed renal collecting system and yields better ultrasonographic imaging by increasing the amount of fluid surrounding the calculi. The potential usages of this technique include ultrasound localization for percutaneous stone extraction and during ultrasonographic monitoring of stones treated by extracorporeal shock-wave lithotripsy (ESWL).
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http://dx.doi.org/10.1016/s0090-4295(91)80361-a | DOI Listing |
Int J Mol Sci
November 2024
Seaweed Research Group, School of Health, University of the Sunshine Coast, Maroochydore, QLD 4558, Australia.
() double-stranded RNA binding (DRB) proteins DRB1, DRB2 and DRB4 perform essential roles in microRNA (miRNA) production, with many of the produced miRNAs mediating aspects of the molecular response of to abiotic stress. Exposure of the , and mutants to mannitol stress showed to be the most sensitive to this form of osmotic stress. Profiling of the miRNA landscapes of mannitol-stressed , and seedlings via small RNA sequencing, and comparison of these to the profile of mannitol-stressed wild-type plants, revealed that the ability of the and mutants to mount an appropriate miRNA-mediated molecular response to mannitol stress was defective.
View Article and Find Full Text PDFInt J Mol Sci
September 2024
Neuroimaging and Biotechnology Laboratory (NOBEL), Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), Hospital Clínico Universitario, Rúa Travesa da Choupana s/n, 15706 Santiago de Compostela, Spain.
The blood-brain barrier (BBB) is essential for protection and plays a crucial role in chronic neurological disorders like small-vessel disease and Alzheimer's disease. Its complexity poses significant challenges for effective diagnostics and treatments, highlighting the need for novel animal models and comprehensive BBB dysfunction studies. This study investigates chronic BBB dysfunction induction using osmotic disruption via mannitol in healthy adult male Sprague Dawley rats over 12 weeks.
View Article and Find Full Text PDFJ Ethnopharmacol
March 2024
School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Electronic address:
Ethnopharmacological Relevance: Mailuo shutong pill (MLST) has been widely used in clinical treatment of superficial thrombotic phlebitis (STP). Nevertheless, the major active components of MLST and the mechanism of synergistic action have not been reported.
Aim Of The Study: The present study aimed to evaluate the improving effects and the underlying mechanism of MLST on mannitol-induced STP in rabbits.
Prostaglandins Other Lipid Mediat
October 2023
Institute of Environmental Medicine, Karolinska Institutet, Sweden; Centre for Allergy Research, Karolinska Institutet, Sweden. Electronic address:
Exercise-induced bronchoconstriction (EIB) is thought to be triggered by increased osmolarity at the airway epithelium. The aim of this study was to define the contractile prostanoid component of EIB, using an ex vivo model where intact segments of bronchi (inner diameter 0.5-2 mm) isolated from human lung tissue and subjected to mannitol.
View Article and Find Full Text PDFHear Res
December 2022
Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada; Department of Otolaryngology Head & Neck Surgery, Sunnybrook Health Sciences Centre, Toronto, Canada. Electronic address:
Cisplatin, a chemotherapeutic medication, remains in the cochlea indefinitely, causing permanent hearing loss. Mannitol, a diuretic medication, has been shown to increase the permeability of the blood labyrinth barrier (BLB). We hypothesize that mannitol increases the permeability of the BLB and therefore increases the rate of entry and egression of cisplatin and entry of otoprotective agents.
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