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The simultaneous occurrence of more than two types of neoplasms is rare due to their significant phenotypic differences. Thyroid carcinoma is regularly associated with genetic alterations and endocrine syndromes. However, the etiology of the forms of papillary thyroid carcinoma (PTC)/medullary thyroid carcinoma (MTC) is still not fully understood.
View Article and Find Full Text PDFMixed Medullary-Papillary Thyroid Carcinoma with Mixed Lymph Node Metastases: a Case Report and Review of the Literature.
Cancer Manag Res
September 2024
Department of Thyroid and Breast Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Papillary thyroid and medullary thyroid cancers are two distinct types of thyroid neoplasms. Co-occurrence of these cancers is rare, especially in mixed tumours with lymph node metastases. A 66-year-old man presented with a thyroid tumour.
View Article and Find Full Text PDFKey Clinical Message: The occurrence of simultaneous multifocal papillary thyroid carcinoma and mixed medullary-papillary carcinoma, as far as we know, has not been previously described. We suggest the surgical approach to be driven by the medullary component.
Abstract: Patient underwent total thyroidectomy with central compartment lymph node dissection.
Features of mixed medullary thyroid tumors: An NCDB analysis of clinicopathologic characteristics and survival.
Am J Surg
July 2023
Department of Surgery, Cooper University Hospital, Camden, NJ, 01803, USA. Electronic address:
Background: Mixed medullary-papillary thyroid carcinoma (MMPTC) and mixed medullary-follicular thyroid carcinoma (MMFTC) are rare variants with little known regarding behavior and prognosis.
Methods: Using the National Cancer Database (NCDB), demographics, clinicopathologic features, treatment, and overall survival (OS) from patients with MMPTC and MMFTC were compared to more prevalent subtypes.
Results: There were 296,101 patients: 421 MMPTC (0.
Mixed medullary-papillary thyroid carcinoma with mixed lymph node metastases: A case report.
Clin Case Rep
May 2021
Serviço de Endocrinologia do Instituto Português de Oncologia do Porto Francisco Gentil Porto Portugal.
Mixed medullary-follicular-derived carcinoma is a very rare event. It is extremely important to make the correct diagnosis, due to prognostic and treatment implications. A genetic study of these patients is advisable to exclude the presence of MEN 2.
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