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Multi-metal mixture exposure and cognitive function in urban older adults: The mediation effects of thyroid hormones.
Ecotoxicol Environ Saf
January 2025
Department of Sanitary Chemistry, School of Public Health, Guangxi Medical University, Nanning 530021, China; Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, Guilin Medical University, China. Electronic address:
The existing studies on the association between multi-metal mixture exposure and cognitive function in the older adults are limited and controversial, with no studies considering the mediating effect of thyroid hormones on the connection between them. This study of 441 urban older adults assessed 21 urinary metal levels and cognitive function using the Mini-Mental State Examination (MMSE). Urinary metal levels were measured via inductively coupled plasma mass spectrometry (ICP-MS), and thyroid hormones levels were obtained from medical records.
View Article and Find Full Text PDFAdsorption structures and bonding states of cesium and barium adsorbed on various sites of vermiculite.
Sci Total Environ
January 2025
Department of Earth and Planetary Science, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan; Isotope Science Center, The University of Tokyo, Bunkyo, Tokyo 113-0032, Japan. Electronic address:
The adsorption reaction on clay minerals is crucial for understanding the environmental behavior of various cations, including cesium (Cs). However, its details remain unclear because of multiple adsorption sites of the clay minerals, a significant difference between concentrations in the atomic-scale experiments and the actual environment, and difficulties of evaluating bonding states of the adsorbed cations. It is expected that systematic experiments at the atomic-scale with a wide concentration range and application of density functional theory (DFT) calculations overcome the problems and bring crucial insights to link laboratory experiment results with environmental sample analysis.
View Article and Find Full Text PDFThe First Report of Environmental Exposure to Barium in 10 Localities Close to Industrial Areas and Ports in the Amazon.
Int J Environ Res Public Health
January 2025
Programa de Pós-Graduação em Saúde Coletiva, Instituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro (IESC/UFRJ), Rio de Janeiro 21941-901, Brazil.
Environmental exposure to metallic contaminants such as barium (Ba) is a worldwide concern, as these metals can even be toxic to the human body. Data on different sources of exposure to Ba and possible routes of entry are important for preventing adverse health effects. Blood Ba levels were evaluated in 10 localities in the cities of Barcarena and Abaetetuba in the Amazon.
View Article and Find Full Text PDFPuerarin Promotes the Migration and Differentiation of Myoblasts by Activating the FAK and PI3K/AKT Signaling Pathways.
Biology (Basel)
January 2025
NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Puerarin, a flavonoid compound present in the roots of radix , contributes to the development of tissues such as bone and nerve, but its role in skeletal muscle regeneration remains unclear. In this study, we employed C2C12 myoblasts and barium chloride (BaCl)-based muscle injury models to investigate the effects of puerarin on myogenesis. Our study showed that puerarin stimulated the migration and differentiation of myoblasts in vitro.
View Article and Find Full Text PDFA new approach for assessing the radioecological risk associated with the legacy discharge of oil derived natural radioactivity in the UK North Sea.
Mar Pollut Bull
January 2025
School of Life Sciences, University of Essex, Colchester CO4 3SQ, UK.
Although oil and gas (O&G) derived produced waters and drill cuttings are known to contain enhanced levels of naturally occurring radium-228 (Ra) and radium-226 (Ra), most relevant ecological impact assessments have excluded radiological hazards and focus on other important contaminants, such as hydrocarbons and metals. Also, due to restricted access to the delimiting safety zone around operational O&G platforms, the few previous radioecological risk assessment studies have been conducted using seawater samples collected far from the main discharge point and applying default dilution and transfer factors to estimate concentrations of contaminants in biota. In this case study, sediment cores were collected close to a former O&G platform, Northwest Hutton (NWH), that used to be in the UK North Sea (61.
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