Background And Objective: Obesity in children is characterized by a rapid gain of weight starting at an age of 4 to 5 years. We investigated whether low threshold prevention prevented a further increase of the Standard-Deviation-Score of the BMI (BMI SDS) in children with impending obesity.
Patients And Methods: The network CrescNet collected data from more than 300,000 children. We selected 365 children with impending obesity (age 4 to 7 years). After randomisation the study population was divided into an intervention group (180 children) and a control group (185 not informed children). The paediatrician carried out a low threshold intervention consisted of an age-adapted nutrition and exercise program to inspire the awareness of the adequate nourishment and motion.
Results: 59 children of the intervention group opted for a participation and 49 of them took part to the end of the study. This study population stabilized their BMI SDS (p < 0.025). The children randomised in the intervention group who were not interested to participate, and the children of the control group increased their BMI SDS within the observation period of one year (p < 0.001, p = 0.002). According to nutrition diaries a decrease energy intake of the participants of the intervention group was detected. The percentage of protein intake was particularly remarkable, amounting to 363 % fulfillment of demand at the beginning of the study and 274 % at the end. A regression analysis suggests that an intervention and also the approval to take part in the study had a significant influence on changes in BMI SDS.
Conclusion: A low threshold intervention in early childhood could successfully prevent an increase of obesity.
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http://dx.doi.org/10.1055/s-0028-1105883 | DOI Listing |
Acta Clin Belg
January 2025
Erzurum Regional Training and Research Hospital, Department of Emergency Medicine, Erzurum, Turkey.
Objectives: In this study, the capacity of End-tidal carbon dioxide (EtCO2) levels to predict the risk of major cardiovascular events (MACE) in patients diagnosed with acute coronary syndrome and the relationship between risk scoring systems (TIMI, GRACE, HEART) and EtCO2 values were examined.
Methods: EtCO2 values of the patients in the study were measured with a capnography device. Each patient's MACE status was recorded.
JAMA Netw Open
January 2025
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Importance: During buprenorphine treatment for opioid use disorder (OUD), risk factors for opioid relapse or treatment dropout include comorbid substance use disorder, anxiety, or residual opioid craving. There is a need for a well-powered trial to evaluate virtually delivered groups, including both mindfulness and evidence-based approaches, to address these comorbidities during buprenorphine treatment.
Objective: To compare the effects of the Mindful Recovery Opioid Use Disorder Care Continuum (M-ROCC) vs active control among adults receiving buprenorphine for OUD.
JAMA Netw Open
January 2025
Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Importance: Secondary lymphedema is a common, harmful side effect of breast cancer treatment. Robust risk models that are externally validated are needed to facilitate clinical translation. A published risk model used 5 accessible clinical factors to predict the development of breast cancer-related lymphedema; this model included a patient's mammographic breast density as a novel predictive factor.
View Article and Find Full Text PDFTransl Vis Sci Technol
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Purpose: This study investigates the association between visual function and retinal vasculature metrics, particularly perfusion capacity (PC), in eyes with idiopathic epiretinal membrane (iERM), using optical coherence tomography angiography (OCTA).
Methods: This retrospective study includes 30 eyes from 30 iERM patients who had surgery, with a three-month follow-up period. In addition, 28 eyes from 28 healthy individuals served as a control group.
Langmuir
January 2025
Department of Chemical Engineering and Materials Research Institute, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
The chemical reactivity of glass surfaces is often studied with elemental analysis techniques, and although such characterization methods provide insights on compositional changes from exposure to specific chemical conditions, molecule-specific chemical reactions are not determined unambiguously. This study demonstrates the use of reflection-absorption infrared spectroscopy (RAIRS) to detect molecular species on alkali-free boroaluminosilicate and alkali aluminosilicate glasses, using acetic acid vapor as a model reactant to probe reaction sites at the surface with or without pretreatment by aqueous solutions of varied pH. With the assistance of the theoretical calculation of spectral changes based on refractive indices of bulk materials, it was possible to identify the molecular species being removed and produced at the glass surface.
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