[Hygienic risk factors of congenital malformations].

The frequency of multiple congenital malformations, central nervous system and genital malformations were found to be associated to the magnitude and duration of ecological load. Xenobiotics identified in the ambient air of a large industrial center pose an increased risk for antenatal malformations. The largest number of statistically significant correlation coefficients was established between the study variables at a delay lag of 2 years. It is assumed that high ambient air pollution adversely affects the mechanisms of inheritance in future parents long before birth of a child.