Chromatin regulation plays an important role in brain development and the generation of phenotypic diversity. In this issue of Neuron, Jakobsson et al. find that disruption in neurons of KAP1, a key component of transcriptional repressor complexes in the brain, results in increased anxiety-like behavior and sensitivity to stress.
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| http://dx.doi.org/10.1016/j.neuron.2008.12.002 | DOI Listing |
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