[Association of post transplantation diabetes mellitus to active human cytomegalovirus infection and preoperative hepatitis B virus infection: analysis of 75 cases].

Zhonghua Yi Xue Za Zhi

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou 310003, China.

Published: July 2008

Objective: To investigate the relationship of post transplantation diabetes mellitus (PTDM) to active human cytomegalovirus (HCMV) infection and to preoperative hepatitis B virus (HBV) infection respectively.

Methods: The clinical data of 75 patients with liver transplantation was collected to analyze the association of PTDM with active HCMV infection and preoperative HBV infection.

Results: The incidence of PTDM was 17.3% (13/75). The incidence of PTDM in the patients with active HCMV infection after liver transplantation was 23.1% (12/52) significantly higher than that of the patients without active HCMV infection (4.3%, 1/23, P < 0.05). The incidence of PTDM in the patients with preoperative HBV infection was 21.1%, not significantly different from that of the patients without infection (5.6%, P > 0.05).

Conclusion: PTDM may be related to active HCMV infection after liver transplantation, and unrelated to preoperative HBV infection.

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