Objective: The aim of this study is to determine the efficiency of artificial intelligence in detecting craniocervical junction injuries by using an artificial neural network (ANN) that may be applicable in future studies of different traumatic injuries.
Materials And Methods: Major head trauma patients with Glasgow Coma Scale
Results: A total of 127 patients fulfilling inclusion criteria were included in the study. The mean age of the study patients was 31+/-17.7, 77.2% (n=98) of them were male, 13.4% of the patients (n=17) had craniocervical junction pathologies. About 64.7% (n=11) of these pathologies were detected only by CT; 23.5% (n=4) of them by both craniocervical CT and cervical plain radiography; and 11.8% (n=2) of them only by cervical plain radiography. A logistic regression model had a sensitivity of 11.8% and specificity of 99.1%. Positive predictive value was 66.7% and negative predictive value was 87.9%. Area under the curve for logistic regression model was 0.794 (P=0.000). ANN had a sensitivity of 82.4% and specificity of 100%. Positive predictive value was 100% and negative predictive value was 97.3%. Area under the curve for ANN model was 0.912 (P=0.000).
Conclusion: ANN as an artificial intelligence application seems appropriate for detecting and excluding craniocervical junction injury but it should not replace craniocervical junction CT. However, these findings should lead us to test the applicability of ANN on hard-to-diagnose trauma patients or in constructing clinical decision rules.
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http://dx.doi.org/10.1097/MEJ.0b013e3282fce7af | DOI Listing |
Prep Biochem Biotechnol
January 2025
Department of Biotechnology, Arunai Engineering College, Tiruvannamalai, India.
The L-asparaginase is commercial enzyme used as chemotherapeutic agent in cancer treatment and food processing agent in backed and fried food industries. In the present research work, the artificial intelligence and machine learning techniques were employed for modeling and optimization of fermentation process conditions for enhanced production of L-asparaginase by submerged fermentation of . The experimental L-asparaginase activity obtained using central composite experiment design was used for optimization.
View Article and Find Full Text PDFActa Odontol Scand
January 2025
Electronic and Department of Electronics and Automation, Tekirdag Namik Kemal University, Tekirdag, Turkey.
Objectives: Approximal caries diagnosis in children is difficult, and artificial intelligence-based research in pediatric dentistry is scarce. To create a convolutional neural network (CNN)-based diagnostic system for the prompt and efficient identification of approximal caries in pediatric patients aged 5-12 years.
Materials And Methods: Pediatric patients' digital periapical radiographic images were collected to create a unique dataset.
Brain Struct Funct
January 2025
Laboratoire de Neurosciences Cognitives et Adaptatives, Université de Strasbourg, 67000, Strasbourg, France.
This mini-review explores sexual dimorphism in the ventral midline thalamus, focusing on the reuniens nucleus and its role in behavioral functions. Traditionally linked to tasks such as working memory, cognitive flexibility, fear generalization, and memory consolidation, most studies have been conducted in male rodents. Research comparing the effects of ventral midline thalamus manipulations between female and male rodents is limited.
View Article and Find Full Text PDFCurr Opin Neurol
February 2025
High Dimensional Neurology Group, UCL Queen Square Institute of Neurology, University College London, Russell Square House, Bloomsbury, London, UK.
Purpose Of Review: Though simple in its fundamental mechanism - a critical disruption of local blood supply - stroke is complicated by the intricate nature of the neural substrate, the neurovascular architecture, and their complex interactions in generating its clinical manifestations. This complexity is adequately described by high-resolution imaging with sensitivity not only to parenchymal macrostructure but also microstructure and functional tissue properties, in conjunction with detailed characterization of vascular topology and dynamics. Such descriptive richness mandates models of commensurate complexity only artificial intelligence could plausibly deliver, if we are to achieve the goal of individually precise, personalized care.
View Article and Find Full Text PDFEduc Psychol Meas
January 2025
Faculty of Psychology and Educational Sciences, KU Leuven, Campus KULAK, Kortrijk, Belgium.
Multidimensional Item Response Theory (MIRT) is applied routinely in developing educational and psychological assessment tools, for instance, for exploring multidimensional structures of items using exploratory MIRT. A critical decision in exploratory MIRT analyses is the number of factors to retain. Unfortunately, the comparative properties of statistical methods and innovative Machine Learning (ML) methods for factor retention in exploratory MIRT analyses are still not clear.
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