Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2174/138620708786734253 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Highly efficient removal of diclofenac sodium with polystyrene supported ionic liquid.
Environ Technol
June 2024
School of Environmental and Municipal Engineering, North China University of Water Resources and Electric Power, Zhengzhou, People's Republic of China.
Diclofenac sodium (DS) is now recognized as an emerging pollutant, and is one of the most commonly discovered pharmaceuticals in water due to its extensive application in the clinic. This study examined the adsorption performance of a polystyrene-supported ionic liquid material (PS-[Nim][Cl]) for the removal of diclofenac sodium (DS) from water. The data from this study showed that maximum removal of DS can be achieved even in conditions with significant pH and temperature fluctuations.
View Article and Find Full Text PDFEngineering the Hydrophobic Microenvironment in Polystyrene-Supported Artificial Catalytic Triad Nanocatalysts: An Effective Strategy for Improving Catalytic Performance.
Langmuir
April 2023
Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Wuhan 430062, China.
Hydrophobic environments have been identified as one of the main parameters affecting the catalytic performance of artificial catalytic triads but are often ignored as an approach to engineering these catalysts. Here, we have developed a simple yet powerful strategy to engineer the hydrophobic environment in polystyrene-supported artificial catalytic triad (PSACT) nanocatalysts. Hydrophobic copolymers containing either oligo(ethylene glycol) side chains or hydrocarbon side chains were synthesized and used for the preparation of nanocatalysts through nanoprecipitation in aqueous media.
View Article and Find Full Text PDFSupported Palladium-Catalyzed Tandem Synthesis of 2-(Alkylamino/amino)-3-arylquinazolin-4(3H)-ones Employing CO Source.
Chem Asian J
March 2023
Chemical Technology Division, CSIR- Institute of Himalayan Bioresource Technology, Palampur, 176061, H.P, India.
Herein, we demonstrated heterogeneous and recyclable polystyrene-supported palladium (Pd@PS) nanoparticles (NPs) catalyzed tandem addition and intramolecular aminocarbonylative cyclization approach for the synthesis of potentially bioactive 2-(alkylamino/amino)-3-arylquinazolin-4(3H)-one analogues from 2-iodophenylcarbodiimides employing amines as nucleophiles and oxalic acid as an ex-situ CO alternative. Various cyclic/acyclic primary and secondary amines were employed and selectively produced substituted 2-(alkylamino)-3-arylquinazolin-4(3H)-ones in good to excellent yields. In addition, we extended the developed strategy to fix two ammonium carbamate and oxalic acid as gaseous NH and CO sources respectively, for the synthesis of 2-amino-3-arylquinazolin-4(3H)-one derivatives.
View Article and Find Full Text PDFDevelopment of Immobilized Carreira (Phosphoramidite, Olefin) Ligands and Application in Iridium-Catalyzed Asymmetric Allylic Amination.
J Org Chem
February 2023
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology (BIST), E-43007 Tarragona, Spain.
A family of polystyrene-supported (phosphoramidite, olefin) ligands -, based on the original design by Defieber and Carreira, has been developed and applied in iridium-catalyzed asymmetric allylic amination of unmasked allylic alcohols (27 examples, up to 99% ee). Among them, functional resins and exhibit important advantages such as easy preparation, ligand recyclability, and easy handling for sequential use. As a distinctive advantage, the catalytic use of the iridium complexes of and allows the straightforward reuse of a high percentage of the expensive iridium metal involved in the complexes, which is not achievable under homogeneous conditions with the corresponding monomeric complexes.
View Article and Find Full Text PDFHoreau amplification in the sequential acylative kinetic resolution of (±)-1,2-diols and (±)-1,3-diols in flow.
Org Biomol Chem
April 2021
EaStCHEM, School of Chemistry, University of St Andrews, St Andrews, Fife KY16 9ST, UK.
The sequential acylative kinetic resolution (KR) of C2-symmetric (±)-1,2-syn and (±)-1,3-anti-diols using a packed bed microreactor loaded with the polystyrene-supported isothiourea, HyperBTM, is demonstrated in flow. The sequential KRs of C2-symmetric (±)-1,2-syn and (±)-1,3-anti-diols exploits Horeau amplification, with each composed of two successive KR processes, with each substrate class significantly differing in the relative rate constants for each KR process. Optimisation of the continuous flow set-up for both C2-symmetric (±)-1,2-syn and (±)-1,3-anti-diol substrate classes allowed isolation of reaction products in both high enantiopurity and yield.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!