AI Article Synopsis
- The study assessed the effectiveness of using MRI and 18F-FDG PET-CT in diagnosing and planning radiotherapy for head and neck cancer in 35 patients.
- The comparison of images from MRI and CT showed a decrease in interobserver variation for parotid glands and target volumes in a significant number of cases.
- Additionally, the application of 18F-FDG PET-CT led to changes in treatment plans for some patients, suggesting it can enhance planning accuracy under specific conditions.
Article Abstract
Background: The use of a single MRI and 18F-fluoro deoxyglucose positron emission tomography-CT (18F-FDG PET-CT) was evaluated, both in diagnostic procedure and radiotherapy planning, in patients with head and neck cancer.
Methods: Thirty-five patients with nasopharyngeal and oropharyngeal tumors were studied. The MRI and 18F-FDG PET-CT were used for both diagnostic work-up and gross tumor volume and critical structure delineation. The interobserver variation (IOV) of volumes determined on MRI and CT by a radiotherapist and by a radiologist were compared as well as their impact on dose distribution.
Results: The CT-MRI decreased the IOV of parotid glands in 12 of 35 and target volume in 15 of 35 patients. The use of 18F-FDG PET-CT changed the treatment design in 6 of 21 patients.
Conclusions: Diagnostic imaging performed in the treatment position can improve the accuracy of radiotherapy planning in case of intracranial tumor extension, heavy dental work, or contraindication for contrast-enhanced CT, but not in the absence of these conditions.
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| http://dx.doi.org/10.1002/hed.21005 | DOI Listing |
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