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A novel and convenient protocol for synthesis of pyridazines. | LitMetric

A new flexible strategy for the synthesis of diversely functionalized pyridazines from 4-chloro-1,2-diaza-1,3-butadienes and active methylene compounds is reported. The high chemoselectivity of this approach offers access to structural precursors of GABA-A antagonist analogues.

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http://dx.doi.org/10.1021/ol802432zDOI Listing

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