The investigation includes results of treatment of 456 elderly and senile patients. The patients were divided into 3 groups. The main group consisted of 178 patients treated with live bacterial preparation sporobacterin included in the complex therapy. The first control group (171 patients) and the second (107 patients) were given antibiotics in the complex therapy. If there were no medical effect in the patients of the main and first control groups percutaneous and transhepatic cholecystostomy were made under US control. In the second group there was operation of cholecystectomy. In addition to generally accepted methods of assessing the state of the patients, the leukocytic index of intoxication, index of organism resistance and index of blood leukocyte shift were investigated. High anti-inflammatory effect of sporobacterin was proved in treatment of acute cholecystitis in elderly and senile patients, especially when using percutaneous and transhepatic cholecystostomy.
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