Objective: Depression is often accompanied by increased visceral adipose tissue (VAT), stress, enlarged adrenal glands, and an increased risk of cardiovascular disease. VAT turn-over is regulated by adrenal stress hormones such as cortisol. Aim of this study was to investigate the relationship between the adrenal volume as a marker for long-term stress and the volume fractions of several body fat compartments in healthy and depressive women.
Methods: Ten depressive and 12 healthy women were investigated. Fat compartments (VAT, VAT in the upper abdomen, subcutaneous adipose tissue (SCAT), and adrenal volume) were measured by MRI.
Results: Depressive women revealed more VAT in the upper abdomen than the healthy. There was a significant correlation of age and Body Mass Index (BMI) with the visceral adipose tissue volume and adrenal gland size. In a partial correlation, Beck Depression Inventory (BDI) was correlated with VAT in the upper abdomen (r = 0.45, p < 0.05).
Conclusions: The increase of adrenal volume and VAT and the correlation of BDI with VAT in the upper abdomen support the hypothesis of long-term production of stress hormones in depression. This study is a further step toward describing morphologic substrates of depression in endocrine organs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2190/PM.38.3.a | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Objective: Smartphone applications (apps) with optical imaging capabilities are transforming the field of physical anthropometry; digital measurements of body size and shape in clinical settings are increasingly feasible. Currently available apps are usually designed around the capture of two-dimensional images that are then transformed with app software to three-dimensional (3D) avatars that can be used for digital anthropometry. The aim of the current study was to compare waist circumference (WC), hip circumference (HC), four other circumferences (right/left upper arm, thigh) and WC/HC evaluated with a novel high-precision 3D smartphone app to ground-truth measurements made with a flexible tape by a trained anthropometrist.
View Article and Find Full Text PDFInfluence of visceral adipose tissue on the accuracy of tumor T-staging of gastric cancer in preoperative CT.
Jpn J Radiol
November 2024
Department of Pathology, Wuxi No. 2 People's Hospital, Wuxi, Jiangsu, China.
Article Synopsis
- The study aimed to assess how visceral adipose tissue (VAT) area and density influence the accuracy of tumor T-staging in gastric cancer using preoperative CT scans.
- A total of 136 gastric cancer patients were divided into two groups based on the accuracy of their T-staging determined by preoperative CT and postoperative pathology.
- Results showed that patients with accurate staging had a larger VAT area and lower density, and those with a smaller VAT area or tumors in the upper stomach were more likely to have staging errors.
Glycerol Handling in Paired Visceral and Subcutaneous Adipose Tissues in Women with Normal Weight and Upper-Body Obesity.
Int J Mol Sci
August 2024
Department of Biomedicine, Aarhus University, 8200 Aarhus, Denmark.
In adipose tissue, reduced expression of the glycerol channel aquaporin 7 (AQP7) has been associated with increased accumulation of triglyceride. The present study determines the relative protein abundances of lipolytic enzymes, AQP7, and cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) in paired mesenteric and omental visceral adipose tissue (VAT) and abdominal and femoral subcutaneous adipose tissue (SAT) in women with either normal weight or upper-body obesity. No differences in the expression of hormone-sensitive lipase (HSL) or AQP7 were found between the two groups in the four depots.
View Article and Find Full Text PDFCan revenue collection for public funding in health care be progressive? An assessment of 29 Countries.
Health Policy
October 2024
Faculty of Management, Prague University of Economics and Business, Jarošovská 1117/II 377 01, Jindřichův Hradec, Czech Republic.
Most research on health care equity focuses on accessing services, with less attention given to how revenue is collected to pay for a country's health care bill. This article examines the progressivity of revenue collection among publicly funded sources: income taxes, social insurance (often in the form of payroll) taxes, and consumption taxes (e.g.
View Article and Find Full Text PDFThe effect of video-assisted training on upper extremity problems and functions after rotator cuff repair: a randomized controlled trial.
Turk J Med Sci
May 2024
Department of Orthopedics and Traumatology, Mersin University, Medicine Faculty, Mersin, Turkiye.
Background/aim: The shoulder is the most mobile joint in the body, and is frequently exposed to injuries. The applied surgical treatments, protection of the shoulder after surgery, care in the use of the shoulder in activities of daily living (ADLs) and gradual exercise programs are all vital to the recovery process. The present study investigates the effect of video-assisted training (VAT) on upper extremity complications and functions after rotator cuff repair (RCR).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!