Diagnostic procedures for skin melanoma in regional lymph nodes were compared in 250 patients. Doppler effect examination and sentinel biopsy were carried out in 60 patients with primary skin melanoma and clinically intact lymph nodes. Identical examination and regional lymphadenectomy were used in 80 patients with clinically detectable metastases to regional lymph nodes. The same procedures were performed in 110 healthy controls. Histological findings fully confirmed Doppler effect evidence. Regional lymphadenectomy was indicated only in patients with verified Doppler effect-related metastatic lesions to the lymph nodes.
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