The rise of allergic diseases warrants an investigation of various environmental factors that are able to influence man negatively. By interacting with the human organism, bacteria and their decomposition products are well-known to stimulate different immunological reactions. The 24-month study has indicated that the total bacterial contamination of dust and the typical diversity of microbes depend on the season. In winter the occurrence ofgram-negative bacteria is high. The latter is indicative of that the dust of flats may contain high levels of endotoxin and thus the less comfort of life in the individuals who are genetically predisposed to hypersensitivity.

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