Hospital discharge datasets are a key source for estimating the incidence of non-fatal injuries. While hospital records usually document injury diagnosis (e.g. traumatic brain injury, femur fracture, etc.) accurately, they often contain poor quality information on external causes (e.g. road traffic crashes, falls, fires, etc.), if such data is recorded at all. However, estimating incidence by external causes is essential for designing effective prevention strategies. Thus, we developed a method for estimating the number of hospital admissions due to each external cause based on injury diagnosis. We start with a prior probability distribution of external causes for each case (based on victim age and sex) and use Bayesian inference to update the probabilities based on the victim's injury diagnoses. We validate the method on a trial dataset in which both external causes and injury diagnoses are known and demonstrate application to two problems: redistribution of cases classified to ill-defined external causes in one hospital data system; and, estimation of external causes in another hospital data system that only records nature of injuries. In comparison with age-sex proportional distribution (the method usually employed), we found the Bayesian method to be a significant improvement for generating estimates of incidence for many external causes (e.g. fires, drownings, poisonings). But the method, performed poorly in distinguishing between falls and road traffic injuries, both of which are characterized by similar injury codes in our datasets. While such stop gap methods can help derive additional information, hospitals need to incorporate accurate external cause coding in routine record keeping.
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http://dx.doi.org/10.1016/j.aap.2008.07.002 | DOI Listing |
Eur J Nucl Med Mol Imaging
January 2025
Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria.
Purpose: Advancements of deep learning in medical imaging are often constrained by the limited availability of large, annotated datasets, resulting in underperforming models when deployed under real-world conditions. This study investigated a generative artificial intelligence (AI) approach to create synthetic medical images taking the example of bone scintigraphy scans, to increase the data diversity of small-scale datasets for more effective model training and improved generalization.
Methods: We trained a generative model on Tc-bone scintigraphy scans from 9,170 patients in one center to generate high-quality and fully anonymized annotated scans of patients representing two distinct disease patterns: abnormal uptake indicative of (i) bone metastases and (ii) cardiac uptake indicative of cardiac amyloidosis.
Discov Oncol
January 2025
Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230000, China.
Aim: To construct a predictive model based on the LODDS stage established for patients with late-onset colon adenocarcinoma to enhance survival stratification.
Methods: Late-onset colon adenocarcinoma data were obtained from the public database. After determining the optimal LODDS truncation value for the training set via X-tile software, we created a new staging system by integrating the T stage and M stage.
Clin Spine Surg
January 2025
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine.
Study Design: Retrospective cohort study using prospective database.
Objective: This study aimed to establish a risk-scoring system for predicting severe complications after pyogenic spondylodiscitis surgery.
Summary Of Background Data: Pyogenic spondylodiscitis surgery can cause severe complications.
Int J Dermatol
January 2025
Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
In this paper, the European Academy of Dermatology and Venereology (EADV) Task Force on Quality of Life (QoL) and Patient-Oriented Outcomes presents its position statements on health-related (HR) QoL assessment in epidermolysis bullosa (EB). The EADV TF on QoL and Patient-Oriented Outcomes recommends the use of the EB-specific instrument QOLEB in patients over the age of 10 years and, in addition to the QOLEB, the use of iscorEB-p in moderate-to-severe EB; the IntoDermQoL proxy instrument with its EB-specific module should be used in children aged under 5 years. The EB-specific instrument iscorEB-p, and the dermatology-specific instrument CDLQI may measure HRQoL in children with EB aged from 5 to 10 years.
View Article and Find Full Text PDFInt J Surg
January 2025
Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Background: Integrating comprehensive information on hepatocellular carcinoma (HCC) is essential to improve its early detection. We aimed to develop a model with multi-modal features (MMF) using artificial intelligence (AI) approaches to enhance the performance of HCC detection.
Materials And Methods: A total of 1,092 participants were enrolled from 16 centers.
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