Background: Pharmacy students in the community setting are ideally situated to help patients monitor chronic diseases; however, their beliefs toward monitoring patients' health are not known.
Objectives: Study objectives are to identify relevant survey constructs and survey measures about monitoring beliefs, establish their psychometric properties, and describe students' beliefs about monitoring.
Methods: Four constructs that assess pharmacy students' monitoring beliefs were identified through literature review and pilot research: self-efficacy, outcome expectancies, role beliefs, and mattering. Measures of each construct were adapted or developed. The psychometric properties of each scale were evaluated in fourth year pharmacy students. A confirmatory factor analysis (CFA) was used to provide evidence for the factor structure of the scales and validity. Internal consistency reliability was assessed with Cronbach's alpha. Finally, students' responses were described.
Results: The response rate was 94% (119 of 127 students). A CFA revealed that a 5-factor model with the elimination of 2 questions was a better fitting model than the originally proposed 4-factor model. Reliability was good for scales except the negative outcome expectancies. Overall, students had positive attitudes toward their monitoring role and were "rather sure" they could routinely monitor.
Conclusions: Evidence was provided for the psychometric properties of new measures of monitoring specific self-efficacy, outcome expectancies, and monitoring role orientation, as well as a new measure of general mattering for pharmacy. These instruments have the potential to help pharmacy practice researchers assess pharmacy students' and ultimately pharmacists' beliefs about monitoring.
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http://dx.doi.org/10.1016/j.sapharm.2007.11.001 | DOI Listing |
Bioconjug Chem
January 2025
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-5127, United States.
Red blood cells (RBCs) serve as natural transporters and can be modified to enhance the pharmacokinetics and pharmacodynamics of a protein cargo. Affinity targeting of Factor IX (FIX) to the RBC membrane is a promising approach to improve the (pro)enzyme's pharmacokinetics. For RBC targeting, purified human FIX was conjugated to the anti-mouse glycophorin A monoclonal antibody Ter119.
View Article and Find Full Text PDFJAMA Pediatr
January 2025
Vascular Assessment and Management Service, Department of Anaesthesia and Pain, Queensland Children's Hospital, Children's Health Queensland Hospital and Health Service, Queensland, Australia.
Importance: Pediatric peripheral intravenous catheter (PIVC) insertion can be difficult and time-consuming, frequently requiring multiple insertion attempts and often resulting in increased anxiety, distress, and treatment avoidance among children and their families. Ultrasound-guided PIVC insertion is a superior alternative to standard technique (palpation and visualization) in high-risk patients.
Objective: To compare first-time insertion success of PIVCs inserted with ultrasound guidance compared with standard technique (palpation and visualization) across all risk categories in the general pediatric hospital population.
JAMA Netw Open
January 2025
Amazon Health Services, Seattle, Washington.
Importance: Medication nonadherence imposes high morbidity, mortality, and costs but is challenging to address given its multiple causes. Subscription models are increasingly used in health care to encourage healthy behaviors; in January 2023, Amazon Pharmacy launched RxPass, a subscription program offering Amazon Prime members (hereafter, company members) in 45 states access to 60 common generic medications for a flat $5 monthly fee.
Objective: To evaluate the associations of program enrollment with medication refills, days' supply, and out-of-pocket costs.
Drug Saf
January 2025
Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, 5000, Odense C, Denmark.
Introduction: Large administrative healthcare databases can be used for near real-time sequential safety surveillance of drugs as an alternative approach to traditional reporting-based pharmacovigilance. The study aims to build and empirically test a prospective drug safety monitoring setup and perform a sequential safety monitoring of rofecoxib use and risk of cardiovascular outcomes.
Methods: We used Danish population-based health registers and performed sequential analysis of rofecoxib use and cardiovascular outcomes using case-time-control and cohort study designs from January 2000 to September 2004.
The present study sought to examine the occurrence and correlates of depression, PTSD, and insomnia in a cohort of Palestinian refugees residing in camps located in Jordan during the outbreak of the War on Gaza on Oct.7th.This is a cross-sectional cohort study that employed the convenient sampling method to recruit Palestinian refugees residing in Irbid and Azmi Almufti camps for Palestinian refugees.
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