Luigi Galvani became one of the greatest scientists of the 18th century with his research and the development of his theory on animal electricity. His work was appreciated by many scientists. Nevertheless, it gave rise to one of the most passionate scientific debates in history when Alessandro Volta postulated that Galvani had confused intrinsic animal electricity with small currents produced by metals. This debate would result in the creation of electrophysiology, electromagnetism, electrochemistry and the electrical battery. Galvani responded to each of the postulated theories of Volta giving irrefutable proof of the involvement of electricity in the contraction of muscles. However, his work was subsequently abandoned and silenced for many years but his ideas and theories were finally confirmed by the creation of new instruments and the interest of new scientists who helped position Galvani as the father of electrophysiology.
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http://dx.doi.org/10.1016/j.resuscitation.2008.09.020 | DOI Listing |
ACS Pharmacol Transl Sci
July 2024
Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro 2, Siena 53100, Italy.
J Clin Med
January 2023
National Center for Drug Research and Evaluation, National Institute of Health (ISS), 00161 Rome, Italy.
Neuroendocrine tumors (NETs) are rare neoplasms with a wide spectrum of clinical behavior, from the long survival of well-differentiated NETs to the dismal prognosis of high-grade neuroendocrine carcinomas (NECs), being G3 NETs a recently recognized intermediate entity. While the role of chemotherapy is well established in NECs, data on NETs mostly derives from small studies, experts' opinions, and extrapolating results from small-cell lung cancer studies. This narrative review aims to summarize available evidence about the use of chemotherapy in the setting of G1-2 NETs and G3 NETs.
View Article and Find Full Text PDFInt J Environ Res Public Health
October 2022
INSTM National Interuniversity Consortium of Materials Science and Technology, Research Unit of University of Trieste, 34127 Trieste, Italy.
Background: Standardized methods for testing Viral Filtration Efficiency (VFE) of tissues and devices are lacking and few studies are available on aerosolizing, sampling and assessing infectivity of SARS-CoV-2 in controlled laboratory settings. NanoAg-coated endonasal filters appear a promising aid for lowering viable virus inhalation in both adult and younger populations (e.g.
View Article and Find Full Text PDFInt J Environ Res Public Health
October 2021
Department of Chemical and Pharmaceutical Sciences, University of Trieste, Via L. Giorgieri 1, 34127 Trieste, Italy.
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is mainly transmitted through respiratory droplets, aerosols, or direct contact with fomites from an infected subject. It has been reported that SARS-CoV-2 is stable and viable in aerosol up to 16 h in controlled laboratory conditions. However, the aerosolization conditions varied a lot between the studies.
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