Medical diagnostic accuracies can be improved when the pattern is simplified through representation by important features. The feature vector, which is comprised of the set of all features used to describe a pattern, is a reduced-dimensional representation of that pattern. By identifying a set of salient features, the noise in a classification model can be reduced, resulting in more accurate classification. In this study, a signal-to-noise ratio (SNR) saliency measure was employed to determine saliency of input features of probabilistic neural networks (PNNs) used in classification of two types of electrocardiogram (ECG) beats (normal and partial epilepsy). In order to extract features representing the ECG signals, discrete wavelet transform was used. The PNNs used in the ECG signals classification were trained for the SNR screening method. The application results of the SNR screening method to the ECG signals demonstrated that classification accuracies of the PNNs with salient input features are higher than that of the PNNs with salient and non-salient input features.
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Stroke
January 2025
Center for Brain Recovery, Boston University, MA (M.J.M., E.C., M.S., M.R.-M., S.K.).
Background: Predicting treated language improvement (TLI) and transfer to the untreated language (cross-language generalization, CLG) after speech-language therapy in bilingual individuals with poststroke aphasia is crucial for personalized treatment planning. This study evaluated machine learning models to predict TLI and CLG and identified the key predictive features (eg, patient severity, demographics, and treatment variables) aligning with clinical evidence.
Methods: Forty-eight Spanish-English bilingual individuals with poststroke aphasia received 20 sessions of semantic feature-based naming treatment in either their first or second language.
mLife
December 2024
State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai China.
Optimizing enzyme thermostability is essential for advancements in protein science and industrial applications. Currently, (semi-)rational design and random mutagenesis methods can accurately identify single-point mutations that enhance enzyme thermostability. However, complex epistatic interactions often arise when multiple mutation sites are combined, leading to the complete inactivation of combinatorial mutants.
View Article and Find Full Text PDFAm J Community Psychol
January 2025
Boston College, Chestnut Hill, Massachusetts, USA.
Prior research has assessed the ways in which neighborhoods promote or inhibit children's development but has paid less attention to delineating the particular processes through which neighborhoods are linked to child outcomes. This study combines geospatial data with survey data from the Early Childhood Longitudinal Study Kindergarten Cohort of 2010-2011, a nationally representative sample of kindergarteners followed through 5th grade (N ~ 12,300), to explore how differences in neighborhood resources (parks and services) and stressors (crime and neighborhood disadvantage) are associated with variations in parental inputs-school involvement and provision of out-of-home enrichment activities. Using multilevel models assessing within- and between-family associations, we found mixed evidence concerning how neighborhood features are linked to parental inputs.
View Article and Find Full Text PDFPlant Dis
January 2025
Biotechnology, plant protection, Nongsheng Group C735, Zijin Campus, Zhejiang University, Hangzhou, Zhejiang, China, 310058;
To meet the need of crop leaf disease detection in complex scenarios, this study designs a method based on the computing power of mobile devices that ensures both detection accuracy and real-time efficiency, offering significant practical application value. Based on a comparison with existing mainstream detection models, this paper proposes a target detection and recognition algorithm, TG_YOLOv5, which utilizes multi-dimensional data fusion on the YOLOv5 model. The triplet attention mechanism and C3CBAM module are incorporated into the network structure to capture connections between spatial and channel dimensions of input feature maps, thereby enhancing the model's feature extraction capabilities without significantly increasing the parameter count.
View Article and Find Full Text PDFKorean J Pain
January 2025
Independent Researcher, Vilnius, Lithuania.
Classically, pain can be of a nociceptive or neuropathic nature, which refers to non-neural or neural tissue lesions, respectively. Chronic pain in conditions such as migraine, fibromyalgia, and complex regional pain syndrome (CRPS), is thought to perpetuate without a noxious input. Pain in such patients can be assigned neither to the nociceptive nor neuropathic category.
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