The effect of dietary glycemic index on weight maintenance in overweight subjects: a pilot study.

Obesity (Silver Spring)

Nutrition and Dietetic Research Group, Department of Investigative Medicine, Investigative Science, Imperial College London, London, UK.

Published: February 2009

AI Article Synopsis

  • A low-glycemic index (LGI) diet may help people maintain weight after losing it, according to a study conducted in London.
  • The study involved a weight loss phase followed by a 4-month maintenance phase, with regular assessments of diet compliance and appetite.
  • Despite differences in dietary glycemic index, weight changes in participants following high-glycemic (HGI) or LGI diets were minimal and not significantly different, suggesting that altering GI alone might not impact weight maintenance.

Article Abstract

Evidence suggests that a low-glycemic index (LGI) diet has a satiating effect and thus may enhance weight maintenance following weight loss. This study was conducted at Hammersmith Hospital, London, UK, and assessed the effect of altering diet GI on weight-loss maintenance. It consisted of a weight-loss phase and a 4-month randomized weight maintenance phase. Subjects were seen monthly to assess dietary compliance and anthropometrics. Appetite was assessed bimonthly by visual analogue scales while meal challenge postprandial insulin and glucose concentrations were assessed before and after the intervention. Following a median weight loss of 6.1 (interquartile range: 5.2-7.1) % body weight, subjects were randomized to a high-glycemic index (HGI) (n = 19) or LGI (n = 23) diet. Dietary composition differed only in GI (HGI group: 63.7 +/- 9.4; LGI group: 49.7 +/- 5.7, P < 0.001) and glycemic load (HGI group: 136.8 +/- 56.3; LGI group: 89.7 +/- 27.5, P < 0.001). Groups did not differ in body weight (weight change over 4 months, HGI group: 0.3 +/- 1.9 kg; LGI group: -0.7 +/- 2.9 kg, P = 0.3) or other anthropometric measurements. This pilot study suggests that in the setting of healthy eating, changing the diet GI does not appear to significantly affect weight maintenance.

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http://dx.doi.org/10.1038/oby.2008.533DOI Listing

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