[Aerobic bacteria associated with acute appendicitis in children].

Ann Fr Anesth Reanim

Service d'anesthésie-réanimation, hôpital d'Enfants, Bab Saadoun 1006, Tunis, Tunisie.

Published: January 2009

Objective: The aim of the study was to determine the microbiological profile of acute appendicitis in children.

Study Design: Prospective descriptive study including children hospitalized for acute appendicitis.

Methods: A specimen of the appendice and the peritoneal exudates (if exists) was performed intraoperatively for aerobe bacteriological examination. Anaerobic incubation was not possible in our study.

Results: Eighty children were included. The specimen culture isolated aerobic bacteria in 56 patients (70%). Polymicrobial infection was found in 14 children. Gram-negative bacilli were the most frequently isolated microorganisms (64/70). Escherichia coli was found in 48 children. The resistance rate to amoxicilline-clavulanic acid and to cefazolin was 35%. Pseudomonas aeruginosa susceptible to ticarcillin was detected in seven patients.

Conclusion: In our study, the specimen culture found aerobic bacteria in 70% of cases, especially Gram-negative bacilli. Empiric antibiotherapy in acute complicated appendicitis in children should be efficient against these microorganisms.

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Source
http://dx.doi.org/10.1016/j.annfar.2008.10.015DOI Listing

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