AI Article Synopsis

  • The study highlights the significant presence of non-cognitive symptoms in individuals with dementia, with a prevalence rate of 90.1% among the sample.
  • A specific cluster of symptoms related to apathy was found to be much more common in dementia cases (55.6%) compared to non-cases (0.7%), indicating a strong distinction between the two groups.
  • The findings suggest that these non-cognitive symptoms are not only prevalent but may also lead to a reevaluation of how dementia is understood and diagnosed.

Article Abstract

Objective: Clinical experience and recent population studies suggest that psychopathological, non-cognitive symptoms are both frequent and relevant in dementia.

Method: A representative community sample (n = 4,803 individuals, 55 + years) was interviewed in a two-phase design. The Geriatric Mental Sate (GMS) was used for assessment and cases were diagnosed according to DSM-IV-TR criteria.

Results: The prevalence of non-cognitive symptoms (1 + symptoms) in cases of dementia (n = 223) was 90.1%, and negative-type symptoms were most frequently found. A GMS 'apathy-related symptom cluster' (anergia, restriction of activities and anhedonia) was significantly more frequent in the demented (55.6%) than in non-cases (0.7%; specificity = 99.2%). In both dementia of Alzheimer's type and vascular dementia, number of symptoms tended to be inversely related to severity of dementia, but psychopathological profiles differed.

Conclusion: Non-cognitive, negative-type symptoms are very frequent in cases of dementia living in the community. They have powerful specificity in the distinction with non-cases, and might change current concepts of dementia.

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Source
http://dx.doi.org/10.1111/j.1600-0447.2008.01280.xDOI Listing

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