Syndrome X is defined as anginal chest pain accompanied by objective signs of ischemia on exercise testing but with angiographically normal coronary arteries. The aetiology of this syndrome is still not known. The AIM of this study was to evaluate changes in circadian rhythm of gastric myoelectric activity (MA) and autonomic system (AS) and their correlation with dyspeptic symptoms in SX patients. We studied forty consecutive patients, mean age 46+/-8 yrs with syndrome X and 40 sex-, age- and gender-matched healthy volunteers (47+/-5 yrs). The population of syndrome X patients is heterogeneous combining subgroups with normal and low AS activity with high tonic sympathetic drive. Patients with autonomic dysfunction had a high percent of gastric dysrrhythmia with disturbed sympatho-vagal balance particularly at night. We conclude that dyspeptic symptoms in SX patients with autonomic dysfunction are caused mostly by high adrenergic drive affecting stomach myoelectric activity and inducing gastric dysrrhythmias.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Significance and Related Factors of Infection in Children with Dyspepsia.
Pediatr Gastroenterol Hepatol Nutr
January 2025
Department of Pediatrics, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.
Purpose: is a Gram-negative bacterium that is associated with peptic ulcer disease (PUD) and gastric cancer. However, studies on the endoscopic finding and factors related to infection in children are lacking. This study aimed to evaluate the prevalence and factors associated with infection in children with dyspepsia.
View Article and Find Full Text PDFRandomized clinical trial: the effects of mirtazapine in functional dyspepsia patients.
Therap Adv Gastroenterol
January 2025
Center of Health Management, Qilu Hospital of Shandong University, 107 Wenhuaxi Road, Jinan, Shandong 250012, China.
Background: Functional dyspepsia (FD) is one of the most common gastrointestinal disorders worldwide. Currently, anti-gastric drugs, gastric acid inhibitors, prokinetic drugs, and mucosal protective drugs are widely used in FD patients, however, only a small proportion of patients benefit from these drugs. Studies reported mirtazapine may improve symptoms of FD patients but the efficacy and safety of mirtazapine in the treatment of FD is unclear.
View Article and Find Full Text PDFIMPROVEMENT OF SURGICAL TREATMENT OF ACUTE BILIARY PANCREATITIS.
Georgian Med News
October 2024
3State Higher Medical College named after D. Kalmataev, Semey, Republic of Kazakhstan.
Purpose Of The Study: improving the surgical treatment of biliary pancreatitis by using a universal retractor and improved methods of omentobursostomy with drainage of the omental bursa.
Study Design: Non-randomized controlled clinical trial Material and methods: This study included thirty-nine patients who underwent surgical procedures between October 2022 and September 2023 in Semey, located in the Abay region. The study examined the general characteristics of surgical interventions performed for acute biliary pancreatitis using our proposed treatment methods and devices to improve the outcomes of acute biliary pancreatitis.
Long-term assessment of Helicobacter pylori cagA EPIYA motif changes and pathology outcomes in gastric biopsies of dyspeptic patients: 10-year follow-up.
BMC Gastroenterol
December 2024
Department of Microbiology and Microbial Biotechnology, Faculty of Life Science and Biotechnology, Shahid Beheshti University, Tehran, Iran.
Introduction: Helicobacter pylori exhibit considerable genetic diversity, especially in the cagA gene, which is prone to rearrangement, affecting gastric pathology. This study aims to identify changes in the cagA EPIYA motif patterns and gastric pathology during long-term colonization and to explore how factors such as smoking, alcohol consumption, gender, and age influence these changes.
Methods: Paired formalin-fixed paraffin-embedded (FFPE) gastric biopsies from 100 H.
Diagnostic performance of biopsy-based methods for determination of Helicobacter pylori infection in dyspeptic Mozambican patients.
J Infect Dev Ctries
November 2024
Department of Microbiology, Faculty of Medicine, Universidade Eduardo Mondlane, Maputo, Mozambique.
Background: Helicobacter pylori (H. pylori) is a Gram-negative bacterium capable of colonizing the human stomach, which can lead to various gastrointestinal conditions. Several invasive and non-invasive methods exist for diagnosing H.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!